Sommario

• • ·Table of Contents

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• • ·Editorial Board

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• • ·Information for Readers

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• Editorials

  • ·Recurrent MI and stroke post–acute coronary syndrome: Which is the lesser evil?

    Pagina :191-193

    Shahar Lavi, Vladimír Džavík

    

• Curriculum in Cardiology

  • ·Managing subfertility in patients with heart disease: What are the choices?

    Pagina :29-36

    Matthew Cauldwell, Roshni R. Patel, Philip J. Steer, Lorna Swan, Julian Norman-Taylor, Michael Gatzoulis, Mark R. Johnson

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• Cardiac Safety Research Consortium

  • ·Long-term electrocardiographic safety monitoring in clinical drug development: A report from the Cardiac Safety Research Consortium

    Pagina :156-169

    Jonathan P. Piccini, Richard L. Clark, Peter R. Kowey, Suneet Mittal, Preston Dunnmon, Norman Stockbridge, James A. Reiffel, Mintu P. Turakhia, Paul D. Ziegler, Robert B. Kleiman, Fraz Ismat, Philip Sager

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• Trial Designs

  • ·Assessing MICRO-vascular resistances via IMR to predict outcome in STEMI patients with multivessel disease undergoing primary PCI (AMICRO): Rationale and design of a prospective multicenter clinical trial

    Pagina :37-44

    Massimo Fineschi, Edoardo Verna, Giuseppe Mezzapelle, Davide Bartolini, Giovanni Turiano, Antonio Manari, Katia Lucarelli, Lucia Uguccioni, Alessandra Repetto, Giuseppe Tarantini

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  • ·Clinical decision support for stroke prevention in atrial fibrillation (CDS-AF): Rationale and design of a cluster randomized trial in the primary care setting

    Pagina :45-52

    Lars O. Karlsson, Staffan Nilsson, Emmanouil Charitakis, Magnus Bång, Gustav Johansson, Lennart Nilsson, Magnus Janzon

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  • ·Reduced duration of dual antiplatelet therapy using an improved drug-eluting stent for percutaneous coronary intervention of the left main artery in a real-world, all-comer population: Rationale and study design of the prospective randomized multicenter IDEAL-LM trial

    Pagina :104-111

    Miguel E. Lemmert, Keith Oldroyd, Paul Barragan, Maciej Lesiak, Robert A. Byrne, Evgeny Merkulov, Joost Daemen, Yoshinobu Onuma, Karen Witberg, Robert-Jan van Geuns

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  • ·Rationale and design of the Japan-USA harmonized assessment by randomized, multicenter study of OrbusNEich's combo StEnt (Japan-USA HARMONEE): Assessment of a novel DES platform for percutaneous coronary revascularization in patients with ischemic coronary disease and non–ST-elevation acute coronary syndrome

    Pagina :112-121

    David F. Kong, Shigeru Saito, Shigeru Nakamura, Roxana Mehran, Stephen M. Rowland, Allison Handler, Hussein R. Al-Khalidi, Mitchell W. Krucoff

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  • ·Atrial fibrillation detected by continuous electrocardiographic monitoring using implantable loop recorder to prevent stroke in individuals at risk (the LOOP study): Rationale and design of a large randomized controlled trial

    Pagina :122-132

    Søren Zöga Diederichsen, Ketil Jørgen Haugan, Lars Køber, Søren Højberg, Axel Brandes, Christian Kronborg, Claus Graff, Anders Gaarsdal Holst, Jonas Bille Nielsen, Derk Krieger, Jesper Hastrup Svendsen

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  • ·Toward evidence-based diagnosis of myocarditis in children and adolescents: Rationale, design, and first baseline data of MYKKE, a multicenter registry and study platform

    Pagina :133-144

    Daniel R. Messroghli, Thomas Pickardt, Marcus Fischer, Bernd Opgen-Rhein, Konstantin Papakostas, Dorothée Böcker, André Jakob, Markus Khalil, Goetz C. Mueller, Florian Schmidt, Michael Kaestner, Floris E.A. Udink ten Cate, Robert Wagner, Bettina Ruf, Daniela Kiski, Gesa Wiegand, Franziska Degener, Ulrike M.M. Bauer, Tim Friede, Stephan Schubert, MYKKE Consortium

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  • ·The Design of the Valsartan for Attenuating Disease Evolution in Early Sarcomeric Hypertrophic Cardiomyopathy (VANISH) Trial

    Pagina :145-155

    Carolyn Y. Ho, John J.V. McMurray, Allison L. Cirino, Steven D. Colan, Sharlene M. Day, Akshay S. Desai, Steven E. Lipshultz, Calum A. MacRae, Ling Shi, Scott D. Solomon, E. John Orav, Eugene Braunwald, For the VANISH trial investigators and executive committee

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  • ·Rationale and Design of Family-Based Approach in a Minority Community Integrating Systems–Biology for Promotion of Health (FAMILIA)

    Pagina :170-181

    Sameer Bansilal, Rajesh Vedanthan, Jason C. Kovacic, Ana Victoria Soto, Jacqueline Latina, Johan L.M. Björkegren, Risa Jaslow, Maribel Santana, Samantha Sartori, Chiara Giannarelli, Venkatesh Mani, Roger Hajjar, Eric Schadt, Andrew Kasarskis, Zahi A. Fayad, Valentin Fuster

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  • ·Randomized Evaluation of the Effects of Anacetrapib through Lipid-modification (REVEAL)—A large-scale, randomized, placebo-controlled trial of the clinical effects of anacetrapib among people with established vascular disease: Trial design, recruitment, and baseline characteristics

    Pagina :182-190

    M.J. Landray, L. Bowman, F. Chen, E. Sammons, J.C. Hopewell, K. Wallendszus, W. Stevens, E. Valdes-Marquez, S. Wiviott, C.P. Cannon, E. Braunwald, R. Collins, M.J. Landray (Writing Committtee)

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• Clinical Investigations

  • ·Baseline characteristics of patients enrolled in the Exenatide Study of Cardiovascular Event Lowering (EXSCEL)

    Pagina :1-9

    Robert J. Mentz, M. Angelyn Bethel, Stephanie Gustavson, Vivian P. Thompson, Neha J. Pagidipati, John B. Buse, Juliana C. Chan, Nayyar Iqbal, Aldo P. Maggioni, Steve P. Marso, Peter Ohman, Neil Poulter, Ambady Ramachandran, Bernard Zinman, Adrian F. Hernandez, Rury R. Holman

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  • ·Determinants of operator radiation exposure during percutaneous coronary procedures

    Pagina :10-18

    Alessandro Sciahbasi, Stefano Rigattieri, Alessandro Sarandrea, Maria Cera, Cristian Di Russo, Silvio Fedele, Roberto Patrizi, Silvio Romano, Francesco Rocco Pugliese, Maria Penco, Samir B. Pancholy

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  • ·Association of measured platelet reactivity with changes in P2Y₁₂ receptor inhibitor therapy and outcomes after myocardial infarction: Insights into routine clinical practice from the TReatment with ADP receptor iNhibitorS: Longitudinal Assessment of Treatment Patterns and Events after Acute Coronary Syndrome (TRANSLATE-ACS) study

    Pagina :19-28

    Akshay Bagai, Eric D. Peterson, Lisa A. McCoy, Mark B. Effron, Marjorie E. Zettler, Gregg W. Stone, Timothy D. Henry, David J. Cohen, Phillip J. Schulte, Kevin J. Anstrom, Tracy Y. Wang

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  • ·An examination of the relationship between serum uric acid level, a clinical history of gout, and cardiovascular outcomes among patients with acute coronary syndrome

    Pagina :53-61

    Neha J. Pagidipati, Connie N. Hess, Robert M. Clare, Axel Akerblom, Pierluigi Tricoci, Daniel Wojdyla, Robert T. Keenan, Stefan James, Claes Held, Kenneth W. Mahaffey, Alyssa B. Klein, Lars Wallentin, Matthew T. Roe

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  • ·Day vs night: Does time of presentation matter in acute heart failure? A secondary analysis from the RELAX-AHF trial

    Pagina :62-69

    Peter S. Pang, John R. Teerlink, Leandro Boer-Martins, Claudio Gimpelewicz, Beth A. Davison, Yi Wang, Adriaan A. Voors, Thomas Severin, Piotr Ponikowski, Tsushung A. Hua, Barry H. Greenberg, Gerasimos Filippatos, G. Michael Felker, Gad Cotter, Marco Metra

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  • ·Time to achieving therapeutic international normalized ratio increases hospital length of stay after heart valve replacement surgery

    Pagina :70-77

    Christopher J. Arendt, Joon Hwa Hong, Richard C. Daly, Christopher Scott, Ramila A. Mehta, Kent Bailey, Jyotishman Pathak, Naveen L. Pereira

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  • ·Compliance with guideline-directed therapy in diabetic patients admitted with acute coronary syndrome: Findings from the American Heart Association's Get With The Guidelines–Coronary Artery Disease (GWTG-CAD) program

    Pagina :78-87

    Prakash Deedwania, Tushar Acharya, Kamal Kotak, Gregg C. Fonarow, Christopher P. Cannon, Warren K. Laskey, W. Frank Peacock, Wenqin Pan, Deepak L. Bhatt, GWTG Steering Committee and Investigators

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  • ·Factors associated with rhythm control treatment decisions in patients with atrial fibrillation—Insights from the NCDR PINNACLE registry

    Pagina :88-97

    Anil K. Gehi, Gheorghe Doros, Thomas J. Glorioso, Gary K. Grunwald, Jonathan Hsu, Yang Song, Mintu P. Turakhia, Alexander Turchin, Salim S. Virani, Thomas M. Maddox

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  • ·Percutaneous revascularization in patients treated with thoracic radiation for cancer

    Pagina :98-103

    Erin A. Fender, Jackson J. Liang, Terence T. Sio, John M. Stulak, Ryan J. Lennon, Joshua P. Slusser, Jonathan B. Ashman, Robert C. Miller, Joerg Herrmann, Abhiram Prasad, Gurpreet S. Sandhu

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  • ·Differential occurrence, profile, and impact of first recurrent cardiovascular events after an acute coronary syndrome

    Pagina :194-203

    Connie N. Hess, Robert M. Clare, Megan L. Neely, Pierluigi Tricoci, Kenneth W. Mahaffey, Stefan K. James, John H. Alexander, Claes Held, Renato D. Lopes, Keith A.A. Fox, Harvey D. White, Lars Wallentin, Paul W. Armstrong, Robert A. Harrington, Erik Magnus Ohman, Matthew T. Roe

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• Letter to the Editors

  • ·?-Blocker after acute myocardial infarction

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    Tomoyuki Kawada

    
  • ·Response to letter to the editor by Dr Tomoyuki Kawada

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    Jason E. Allen, Stacey Knight

    
  • ·Letter to Editor

    Pagina :e5

    Ayman Elbadawi, Ahmed S. Abuzaid, Marwan Saad

    
  • ·Reply to comment by Elbadawi et al

    Pagina :e7

    Dinos Verouhis, Peder Sörensson, Andrey Gourine, Loghman Henareh, Jonas Persson, Nawzad Saleh, Magnus Settergren, Martin Sundqvist, Per Tornvall, Nils Witt, Felix Böhm, John Pernow