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• • ·Cover 1

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• • ·Brief Overview of This Month's JACI

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• • ·Table of Contents

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• • ·Editorial Board

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• Reviews and feature articles

  • ·Changing the history of anaphylaxis mortality statistics through the World Health Organization's International Classification of Diseases–11

    Page :627-633

    Luciana Kase Tanno, Robert Chalmers, Ana Luiza Bierrenbach, F. Estelle R. Simons, Bryan Martin, Nicolas Molinari, Isabella Annesi-Maesano, Margitta Worm, Victoria Cardona, Nikolaos G. Papadopoulos, Mario Sanchez-Borges, Lanny J. Rosenwasser, Ignacio Ansontegui, Motohiro Ebisawa, Juan Carlos Sisul, Edgardo Jares, Maximiliano Gomez, Ioana Agache, Peter Hellings, Antonella Muraro, Francis Thien, Ruby Pawankar, James L. Sublett, Thomas Casale, Pascal Demoly, Joint Allergy Academies

    Résumé Résumé Plan Plan  
  • ·ORMDL3 and allergic asthma: From physiology to pathology

    Page :634-640

    Briana James, Sheldon Milstien, Sarah Spiegel

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• The Editors' choice

  • ·The Editors' Choice

    Page :641-642

    Zuhair K. Ballas, Associate Editors of the JACI

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• News beyond our pages

  • ·News beyond our pages

    Page :643-644

    Marc E. Rothenberg, Jean Bousquet

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• Beyond the frontiers

  • ·Cell-based biosensors for immunology, inflammation, and allergy

    Page :645-647

    Maria Eugenia Inda, Mark Mimee, Timothy K. Lu

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• Paradigms and perspectives

  • ·Is there a role for type 2 CD8⁺ T cells in patients with steroid-resistant asthma?

    Page :648-650

    Erwin W. Gelfand, Timothy S.C. Hinks

     

• Editorials

  • ·RAGE-induced asthma: A role for the receptor for advanced glycation end-products in promoting allergic airway disease

    Page :651-653

    Eric B. Brandt, Ian P. Lewkowich

     
  • ·Defining B-cell defects and correlation with complications in patients with common variable immune deficiency

    Page :654-655

    Helen Chapel, Smita Patel

    
  • ·Why do asthma patients cough? New insights into cough in allergic asthma

    Page :656-657

    Daniel Puebla-Neira, William J. Calhoun

     
  • ·Peptide allergen immunotherapy—unraveling new pathways

    Page :658-660

    Ioana Agache

     
  • ·Explaining the link between maternal lipid profiles and food allergy in offspring

    Page :661-662

    Jennifer J. Koplin, Rachel L. Peters

     
  • ·A step in the right direction: Harmonizing measures for use in asthma patient registries

    Page :663-664

    Shyamali Chandrika Dharmage, Dinh Son Bui, Jennifer Perret, Adrian Lowe, Caroline Lodge

     
  • ·Stuck in the MUC: Infinity loop of fucosylation in allergic airway inflammation

    Page :665-667

    Alex KleinJan

     
  • ·Platelets are the Achilles' heel of Wiskott-Aldrich syndrome

    Page :668-670

    Alain Fischer

     

• Asthma and lower airway disease

  • ·Harmonized outcome measures for use in asthma patient registries and clinical practice

    Page :671

    Richard E. Gliklich, Mario Castro, Michelle B. Leavy, Valerie G. Press, Amisha Barochia, Christopher L. Carroll, Julie Harris, Sarah S. Rittner, Robert Freishtat, Reynold A. Panettieri, Giselle S. Mosnaim

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  • ·Toll-like receptor 9–dependent interferon production prevents group 2 innate lymphoid cell–driven airway hyperreactivity

    Page :682

    Christina Li-Ping Thio, Alan Chuan-Ying Lai, Po-Yu Chi, Gill Webster, Ya-Jen Chang

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  • ·Fucosyltransferase 2 induces lung epithelial fucosylation and exacerbates house dust mite–induced airway inflammation

    Page :698

    Aiko Saku, Koichi Hirose, Takashi Ito, Arifumi Iwata, Takashi Sato, Hiroyuki Kaji, Tomohiro Tamachi, Akira Suto, Yoshiyuki Goto, Steven E. Domino, Hisashi Narimatsu, Hiroshi Kiyono, Hiroshi Nakajima

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• Atopic dermatitis and inflammatory skin disease

  • ·Clinical onset of atopic eczema: Results from 2 nationally representative British birth cohorts followed through midlife

    Page :710-719

    Katrina Abuabara, Morgan Ye, Charles E. McCulloch, Alice Sullivan, David J. Margolis, David P. Strachan, Lavinia Paternoster, Yik Weng Yew, Hywel C. Williams, Sinéad M. Langan

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  • ·Walnut antigens can trigger autoantibody development in patients with pemphigus vulgaris through a “hit-and-run” mechanism

    Page :720

    Lan Lin, Timothy P. Moran, Bin Peng, Jinsheng Yang, Donna A. Culton, Huilian Che, Songsong Jiang, Zhi Liu, Songmei Geng, Yuzhu Zhang, Luis A. Diaz, Ye Qian

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• Food allergy and gastrointestinal disease

  • ·Maternal triacylglycerol signature and risk of food allergy in offspring

    Page :729-737

    Xiumei Hong, Liming Liang, Qi Sun, Corinne A. Keet, Hui-Ju Tsai, Yuelong Ji, Guoying Wang, Hongkai Ji, Clary Clish, Colleen Pearson, You Wang, Robert A. Wood, Frank B. Hu, Xiaobin Wang

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• Biologics and immunotherapy

  • ·Immunologic mechanisms of a short-course of Lolium perenne peptide immunotherapy: A randomized, double-blind, placebo-controlled trial

    Page :738-749

    Hanisah Sharif, Iesha Singh, Lubna Kouser, Ralph Mösges, Marie-Alix Bonny, Angeliki Karamani, Rebecca V. Parkin, Nicolas Bovy, Uday Kishore, Abigail Robb, Michael Katotomichelakis, Gabriële Holtappels, Lara Derycke, Francis Corazza, Rémy von Frenckell, Nathalie Wathelet, Jean Duchateau, Thierry Legon, Sabine Pirotton, Stephen R. Durham, Claus Bachert, Mohamed H. Shamji

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  • ·IL-17A inhibition by secukinumab induces early clinical, histopathologic, and molecular resolution of psoriasis

    Page :750-763

    James G. Krueger, Keith A. Wharton, Thomas Schlitt, Maria Suprun, Rebecca I. Torene, Xiaoyu Jiang, Claire Q. Wang, Judilyn Fuentes-Duculan, Nicole Hartmann, Thomas Peters, Irina Koroleva, Rainer Hillenbrand, Martin Letzkus, Xiaojing Yu, Yue Li, Anton Glueck, Anke Hasselberg, Brian Flannery, Mayte Suárez-Fariñas, Wolfgang Hueber

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• Mechanisms of allergy/immunology

  • ·Butyrate ameliorates allergic airway inflammation by limiting eosinophil trafficking and survival

    Page :764-776

    Anna Theiler, Thomas Bärnthaler, Wolfgang Platzer, Georg Richtig, Miriam Peinhaupt, Sonja Rittchen, Julia Kargl, Trond Ulven, Leigh M. Marsh, Gunther Marsche, Rufina Schuligoi, Eva M. Sturm, Akos Heinemann

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  • ·NOD-like receptor family, pyrin domain containing 3 (NLRP3) contributes to inflammation, pyroptosis, and mucin production in human airway epithelium on rhinovirus infection

    Page :777

    Tao Liu, Yu Tao Zhou, Li Qiu Wang, Li Yue Li, Qing Bao, Shuo Tian, Mei Xin Chen, He Xin Chen, Jun Cui, Chun Wei Li

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  • ·Allergen challenge increases capsaicin-evoked cough responses in patients with allergic asthma

    Page :788

    Imran Satia, Richard Watson, Tara Scime, Rachel J. Dockry, Shilpi Sen, James W. Ford, Patrick D. Mitchell, Stephen J. Fowler, Gail M. Gauvreau, Paul M. O'Byrne, Jaclyn A. Smith

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  • ·The receptor for advanced glycation end products is a critical mediator of type 2 cytokine signaling in the lungs

    Page :796

    Timothy N. Perkins, Elizabeth A. Oczypok, Regina E. Dutz, Mason L. Donnell, Michael M. Myerburg, Tim D. Oury

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• Translational and clinical immunology

  • ·Defects in memory B-cell and plasma cell subsets expressing different immunoglobulin-subclasses in patients with CVID and immunoglobulin subclass deficiencies

    Page :809-824

    Elena Blanco, Martín Pérez-Andrés, Sonia Arriba-Méndez, Cristina Serrano, Ignacio Criado, Lucía Del Pino-Molina, Susana Silva, Ignacio Madruga, Marina Bakardjieva, Catarina Martins, Ana Serra-Caetano, Alfonso Romero, Teresa Contreras-Sanfeliciano, Carolien Bonroy, Francisco Sala, Alejandro Martín, José María Bastida, Félix Lorente, Carlos Prieto, Ignacio Dávila, Miguel Marcos, Tomas Kalina, Marcela Vlkova, Zita Chovancova, Ana Isabel Cordeiro, Jan Philippé, Filomeen Haerynck, Eduardo López-Granados, Ana E. Sousa, Mirjam van der Burg, Jacques J.M. van Dongen, Alberto Orfao, EuroFlow PID group

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  • ·Lentiviral gene therapy corrects platelet phenotype and function in patients with Wiskott-Aldrich syndrome

    Page :825-838

    Lucia Sereni, Maria Carmina Castiello, Dario Di Silvestre, Patrizia Della Valle, Chiara Brombin, Francesca Ferrua, Maria Pia Cicalese, Loris Pozzi, Maddalena Migliavacca, Maria Ester Bernardo, Claudio Pignata, Roula Farah, Lucia Dora Notarangelo, Nufar Marcus, Lorella Cattaneo, Marco Spinelli, Stefania Giannelli, Marita Bosticardo, Koen van Rossem, Armando D'Angelo, Alessandro Aiuti, Pierluigi Mauri, Anna Villa

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• Environmental and occupational disease

  • ·Ambient air pollution, asthma drug response, and telomere length in African American youth

    Page :839

    Eunice Y. Lee, Sam S. Oh, Marquitta J. White, Celeste S. Eng, Jennifer R. Elhawary, Luisa N. Borrell, Thomas J. Nuckton, Andrew M. Zeiger, Kevin L. Keys, Angel C.Y. Mak, Donglei Hu, Scott Huntsman, Maria G. Contreras, Lesly-Anne Samedy, Pagé C. Goddard, Sandra L. Salazar, Emerita N. Brigino-Buenaventura, Adam Davis, Kelley E. Meade, Michael A. LeNoir, Fred W. Lurmann, Esteban G. Burchard, Ellen A. Eisen, John R. Balmes

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• Epidemiology and health care delivery

  • ·Home visits for uncontrolled asthma among low-income adults with patient portal access

    Page :846

    Andrea J. Apter, A. Russell Localio, Knashawn H. Morales, Xiaoyan Han, Luzmercy Perez, Alyssa N. Mullen, Marisa Rogers, Heather Klusaritz, John T. Howell, Maryori N. Canales, Tyra Bryant-Stephens

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• Letters to the Editor

  • ·Respiratory syncytial virus nonstructural protein 1 downregulates glucocorticoid receptor expression through miR-29a

    Page :854

    Leiqiong Gao, Shi Mo, Jun Xie, Sisi Chen, Xiang Wen, Xiaoru Long, Luo Ren, Na Zang, Xiaohong Xie, Yu Deng, Jian Luo, Zhengxiu Luo, Zhou Fu, Rosalind L. Smyth, Enmei Liu

     
  • ·Genetic risk scores do not improve asthma prediction in childhood

    Page :857

    F. Nicole Dijk, Charlotte Folkersma, Olena Gruzieva, Ashish Kumar, Alet H. Wijga, Ulrike Gehring, Inger Kull, Dirkje S. Postma, Judith M. Vonk, Erik Melén, Gerard H. Koppelman

     
  • ·Endolysin treatment against Staphylococcus aureus in adults with atopic dermatitis: A randomized controlled trial

    Page :860-863

    Jill de Wit, Joan E.E. Totté, Minke M.F. van Mierlo, Joyce van Veldhuizen, Martijn B.A. van Doorn, Frank H.J. Schuren, Sten P. Willemsen, Luba M. Pardo, Suzanne G.M.A. Pasmans

     
  • ·Janus kinase 1/2 inhibition for the treatment of autoinflammation associated with heterozygous TNFAIP3 mutation

    Page :863

    Ciara M. Mulhern, Ying Hong, Ebun Omoyinmi, Thomas S. Jacques, Felice D'Arco, Cheryl Hemingway, Paul A. Brogan, Despina Eleftheriou

     
  • ·Asthma as an outcome: Exploring multiple definitions of asthma across birth cohorts in the Environmental influences on Child Health Outcomes Children's Respiratory and Environmental Workgroup

    Page :866

    Cynthia M. Visness, Tebeb Gebretsadik, Daniel J. Jackson, Jocelyn Biagini Myers, Suzanne Havstad, Robert F. Lemanske, Tina V. Hartert, Gurjit K. Khurana Hershey, Edward M. Zoratti, Lisa J. Martin, Rachel Miller, Diane R. Gold, Anne Wright, Debra A. Stern, James E. Gern, Christine C. Johnson, Children's Respiratory and Environmental Workgroup

     
  • ·Primary prevention of severe lower respiratory illnesses in at-risk infants using the immunomodulator OM-85

    Page :870

    Peter D. Sly, Sally Galbraith, Zahir Islam, Barbara Holt, Niamh Troy, Patrick G. Holt

     

• Correspondence

  • ·Bronchoprotective tolerance with inhaled corticosteroid/long-acting ?-agonist treatment

    Page :873

    Brian Lipworth, Chris RuiWen Kuo

    
  • ·Reply

    Page :873-874

    Juan Carlos Cardet, Xiaofeng Jiang, Quan Lu, Norma Gerard, Kristen McIntire, Homer A. Boushey, Mario Castro, Vernon M. Chinchilli, Christopher D. Codispoti, Anne-Marie Dyer, Fernando Holguin, Monica Kraft, Stephen Lazarus, Robert F. Lemanske, Njira Lugogo, Dave Mauger, Wendy C. Moore, James Moy, Victor E. Ortega, Stephen P. Peters, Lewis J. Smith, Julian Solway, Christine A. Sorkness, Kaharu Sumino, Michael E. Wechsler, Sally Wenzel, Elliot Israel, AsthmaNet Investigators

    

• Reader services

  • ·Information for Readers

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  • ·News & Notes

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  • ·Continuing Medical Education Calendar

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