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• • ·Table of Contents

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• • ·Editorial Board

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• • ·Information for Readers

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• • ·Use of intensive lipid-lowering therapy in patients hospitalized with acute coronary syndrome: An analysis of 65,396 hospitalizations from 344 hospitals participating in Get With The Guidelines (GWTG)

    Page :418

    Usman Javed, Prakash C. Deedwania, Deepak L. Bhatt, Christopher P. Cannon, David Dai, Adrian F. Hernandez, Eric D. Peterson, Gregg C. Fonarow

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• • ·Correction

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• • ·Correction

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• Editorial

  • ·Challenge of rehospitalizations for heart failure: Potential of natriuretic doses of mineralocorticoid receptor antagonists

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    Robert W. Schrier, Mihai Gheorghiade

     

• Special Articles

  • ·Clinical development of pharmacologic agents for acute heart failure syndromes: A proposal for a mechanistic translational phase

    Page :224-232

    Mihai Gheorghiade, Peter S. Pang, Christopher M. O'Connor, Krishna Prasad, John McMurray, John R. Teerlink, Mona Fiuzat, Hani Sabbah, Michel Komajda

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  • ·Lessons learned from a pediatric clinical trial: The Pediatric Heart Network Angiotensin-Converting Enzyme Inhibition in Mitral Regurgitation Study

    Page :233-240

    Jennifer S. Li, Steven D. Colan, Lynn A. Sleeper, Jane W. Newburger, Victoria L. Pemberton, Andrew M. Atz, Meryl S. Cohen, Fraser Golding, Gloria L. Klein, Ronald V. Lacro, Elizabeth Radojewski, Marc E. Richmond, L. LuAnn Minich

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• Curriculum in Cardiology

  • ·Atrial fibrillation, anticoagulation, fall risk, and outcomes in elderly patients

    Page :241-246

    Matthew B. Sellers, L. Kristin Newby

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  • ·Primary percutaneous coronary intervention for acute myocardial infarction: Is it worth the wait? : The risk-time relationship and the need to quantify the impact of delay

    Page :247-253

    Giuseppe Tarantini, Frans Van de Werf, Claudio Bilato, Bernard Gersh

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• Trial Design

  • ·Design and rationale of the RadIal Vs. femorAL access for coronary intervention (RIVAL) trial: A randomized comparison of radial versus femoral access for coronary angiography or intervention in patients with acute coronary syndromes

    Page :254

    Sanjit S. Jolly, Kari Niemelä, Denis Xavier, Petr Widimsky, Andrzej Budaj, Vicent Valentin, Basil S. Lewis, Alvaro Avezum, Philippe Gabriel Steg, Sunil V. Rao, John Cairns, Susan Chrolavicius, Salim Yusuf, Shamir R. Mehta

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  • ·A randomized, partially blinded, multicenter, active-controlled, dose-ranging study assessing the safety, efficacy, and pharmacodynamics of the REG1 anticoagulation system in patients with acute coronary syndromes: Design and rationale of the RADAR Phase IIb trial

    Page :261

    Thomas J. Povsic, Mauricio G. Cohen, Roxana Mehran, Christopher E. Buller, Christoph Bode, Jan H. Cornel, Jaros?aw D. Kasprzak, Gilles Montalescot, Diane Joseph, William A. Wargin, Christopher P. Rusconi, Steven L. Zelenkofske, Richard C. Becker, John H. Alexander

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  • ·Associations between cardiovascular parameters and uteroplacental Doppler (blood) flow patterns during pregnancy in women with congenital heart disease: Rationale and design of the Zwangerschap bij Aangeboren Hartafwijking (ZAHARA) II study

    Page :269

    Ali Balci, Krystyna M. Sollie, Barbara J.M. Mulder, Monique W.M. de Laat, Jolien W. Roos-Hesselink, Arie P.J. van Dijk, Elly M.C.J. Wajon, Hubert W. Vliegen, Willem Drenthen, Hans L. Hillege, Jan G. Aarnoudse, Dirk J. van Veldhuisen, Petronella G. Pieper

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• Clinical Investigations

  • ·Prehospital triage in the ambulance reduces infarct size and improves clinical outcome

    Page :276-282

    Sonja Postma, Jan-Henk E. Dambrink, Menko-Jan de Boer, A.T. Marcel Gosselink, Gerrit J. Eggink, Henri van de Wetering, Frans Hollak, Jan Paul Ottervanger, Jan C.A. Hoorntje, Evelien Kolkman, Harry Suryapranata, Arnoud W.J. van 't Hof

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  • ·The influence of time from symptom onset and reperfusion strategy on 1-year survival in ST-elevation myocardial infarction: A pooled analysis of an early fibrinolytic strategy versus primary percutaneous coronary intervention from CAPTIM and WEST

    Page :283-290

    Cynthia M. Westerhout, Eric Bonnefoy, Robert C. Welsh, Philippe Gabriel Steg, Florent Boutitie, Paul W. Armstrong

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  • ·Has the ClOpidogrel and Metoprolol in Myocardial Infarction Trial (COMMIT) of early ?-blocker use in acute coronary syndromes impacted on clinical practice in Canada? Insights from the Global Registry of Acute Coronary Events (GRACE)

    Page :291-297

    Jeremy Edwards, Shaun G. Goodman, Raymond T. Yan, Robert C. Welsh, Jan M. Kornder, J. Paul DeYoung, Denis Chauret, Jean-Pierre Picard, Kim A. Eagle, Andrew T. Yan

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  • ·Incidence and clinical consequences of acquired thrombocytopenia after antithrombotic therapies in patients with acute coronary syndromes: Results from the Acute Catheterization and Urgent Intervention Triage Strategy (ACUITY) trial

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    Adriano Caixeta, George D. Dangas, Roxana Mehran, Frederick Feit, Eugenia Nikolsky, Alexandra J. Lansky, Jiro Aoki, Jeffrey W. Moses, Steven R. Steinhubl, Harvey D. White, E. Magnus Ohman, Steven V. Manoukian, Martin Fahy, Gregg W. Stone

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  • ·Pregnancy in women with corrected tetralogy of Fallot: Occurrence and predictors of adverse events

    Page :307-313

    Ali Balci, Willem Drenthen, Barbara J.M. Mulder, Jolien W. Roos-Hesselink, Adriaan A. Voors, Hubert W. Vliegen, Philip Moons, Krystyna M. Sollie, Arie P.J. van Dijk, Dirk J. van Veldhuisen, Petronella G. Pieper

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  • ·Left atrial reverse remodeling and functional improvement after mitral valve repair in degenerative mitral regurgitation: A real-time 3-dimensional echocardiography study

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    Nina Ajmone Marsan, Francesco Maffessanti, Gloria Tamborini, Paola Gripari, Enrico Caiani, Laura Fusini, Manuela Muratori, Marco Zanobini, Francesco Alamanni, Mauro Pepi

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  • ·Certoparin versus unfractionated heparin to prevent venous thromboembolic events in patients hospitalized because of heart failure: A subgroup analysis of the randomized, controlled CERTIFY study

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    Ulrich Tebbe, Sebastian M. Schellong, Sylvia Haas, Horst Eberhard Gerlach, Claudia Abletshauser, Christian Sieder, Peter Bramlage, Hanno Riess

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  • ·A randomized controlled trial evaluating the safety and efficacy of cardiac contractility modulation in advanced heart failure

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    Alan Kadish, Koonlawee Nademanee, Kent Volosin, Steven Krueger, Suresh Neelagaru, Nirav Raval, Owen Obel, Stanislav Weiner, Marc Wish, Peter Carson, Kenneth Ellenbogen, Robert Bourge, Michael Parides, Richard P. Chiacchierini, Rochelle Goldsmith, Sidney Goldstein, Yuval Mika, Daniel Burkhoff, William T. Abraham

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  • ·Effects of n-3 polyunsaturated fatty acids on malignant ventricular arrhythmias in patients with chronic heart failure and implantable cardioverter-defibrillators: A substudy of the Gruppo Italiano per lo Studio della Sopravvivenza nell’Insufficienza Cardiaca (GISSI-HF) trial

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    Andrea A. Finzi, Roberto Latini, Simona Barlera, Maria G. Rossi, Albarosa Ruggeri, Alessandro Mezzani, Chiara Favero, Maria G. Franzosi, Domenico Serra, Donata Lucci, Francesca Bianchini, Roberto Bernasconi, Aldo P. Maggioni, Gianluigi Nicolosi, Maurizio Porcu, Gianni Tognoni, Luigi Tavazzi, Roberto Marchioli

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  • ·Common oral mucosal diseases, systemic inflammation, and cardiovascular diseases in a large cross-sectional US survey

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    Stefano Fedele, Wael Sabbah, Nikos Donos, Stephen Porter, Francesco D'Aiuto

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  • ·Reducing cardiovascular disease risk in medically underserved urban and rural communities

    Page :351-359

    Alfred A. Bove, William P. Santamore, Carol Homko, Abul Kashem, Robert Cross, Timothy R. McConnell, Gail Shirk, Francis Menapace

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  • ·Incidence and clinical outcome of minor surgery in the year after drug-eluting stent implantation: Results from the Evaluation of Drug-Eluting Stents and Ischemic Events Registry

    Page :360-366

    Emmanouil S. Brilakis, David J. Cohen, Neal S. Kleiman, Michael Pencina, Deborah Nassif, Jorge Saucedo, Robert N. Piana, Subhash Banerjee, Michelle J. Keyes, Chen-Hsing Yen, Peter B. Berger

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  • ·Qualitative assessment of neointimal tissue after drug-eluting stent implantation: Comparison between follow-up optical coherence tomography and intravascular ultrasound

    Page :367-372

    Sung Woo Kwon, Byeong-Keuk Kim, Tae-Hoon Kim, Jung-Sun Kim, Young-Guk Ko, Donghoon Choi, Yangsoo Jang, Myeong-Ki Hong

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  • ·Standard versus high loading doses of clopidogrel in Asian ST-segment elevation myocardial infarction patients undergoing percutaneous coronary intervention: Insights from the Korea Acute Myocardial Infarction Registry

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    Cheol Ung Choi, Seung-Woon Rha, Dong Joo Oh, Kanhaiya L. Poddar, Jin Oh Na, Jin Won Kim, Hong Euy Lim, Eung Ju Kim, Chang Gyu Park, Hong Seog Seo, Taek Jong Hong, Jong-Seon Park, Young Jo Kim, Seung Ho Hur, In Whan Seong, Jei Keon Chae, Myeong Chan Cho, Jang Ho Bae, Dong Hoon Choi, Yang Soo Jang, In Ho Chae, Hyo Soo Kim, Chong Jin Kim, Jung Han Yoon, Tae Hoon Ahn, Seung-Jea Tahk, Wook Sung Chung, Ki Bae Seung, Shung Chall Chae, Seung Jung Park, Young Keun Ahn, Myung Ho Jeong

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  • ·Comparison of 2 point-of-care platelet function tests, VerifyNow Assay and Multiple Electrode Platelet Aggregometry, for predicting early clinical outcomes in patients undergoing percutaneous coronary intervention

    Page :383-390

    Young-Guk Ko, Jung-Won Suh, Bo Hyun Kim, Chan Joo Lee, Jung-Sun Kim, Donghoon Choi, Myeong-Ki Hong, Myung-Ki Seo, Tae-Jin Youn, In-Ho Chae, Dong Joo Choi, Yangsoo Jang

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  • ·Impact of baseline thrombocytopenia on the early and late outcomes after ST-elevation myocardial infarction treated with primary angioplasty: Analysis from the Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction (HORIZONS-AMI) trial

    Page :391-396

    Diaa A. Hakim, George D. Dangas, Adriano Caixeta, Eugenia Nikolsky, Alexandra J. Lansky, Jeffrey W. Moses, Bimmer Claessen, Elias Sanidas, Harvey D. White, E. Magnus Ohman, Steven V. Manoukian, Martin Fahy, Roxana Mehran, Gregg W. Stone

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  • ·Temporal changes in the outcomes of patients with diabetes mellitus undergoing percutaneous coronary intervention in the National Heart, Lung, and Blood Institute dynamic registry

    Page :397

    Elizabeth M. Holper, J. Dawn Abbott, Suresh Mulukutla, Helen Vlachos, Faith Selzer, Darren McGuire, David P. Faxon, Warren Laskey, Vankeepuram S. Srinivas, Oscar C. Marroquin, Alice K. Jacobs

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  • ·Clopidogrel loading dose and bleeding outcomes in patients undergoing urgent coronary artery bypass grafting

    Page :404-410

    Nicholas L.M. Cruden, Kristin Morch, Daniel R. Wong, W. Peter Klinke, John Ofiesh, J. David Hilton

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  • ·Factors associated with the physical activity level of children who have the Fontan procedure

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    Patricia E. Longmuir, Jennifer L. Russell, Mary Corey, Guy Faulkner, Brian W. McCrindle

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• Letters to the Editor

  • ·An important indirect drug interaction between dronedarone and warfarin that may be extrapolated to other drugs that can alter gastrointestinal function

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    James A. Reiffel

    
  • ·Shirolkar’s reply to Reiffel’s letter to the editor

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    Shailesh C. Shirolkar