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• • ·Table of Contents

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• • ·Editorial Board

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• • ·Information for Readers

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• Trial Design

  • ·Rationale and design of The Coronary Artery Bypass Grafting Surgery Off or On Pump Revascularization Study: A large international randomized trial in cardiac surgery

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    Andre Lamy, Philip J. Devereaux, Dorairaj Prabhakaran, Shengshou Hu, Leopoldo S. Piegas, Zbynek Straka, Ernesto Paolasso, David Taggart, Fernando Lanas, A. Ruchan Akar, Anil Jain, Nicolas Noiseux, Yongning Ou, Susan Chrolavicius, Jennifer Ng, Salim Yusuf

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  • ·Design of the Trial to Assess Chelation Therapy (TACT)

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    Gervasio A. Lamas, Christine Goertz, Robin Boineau, Daniel B. Mark, Theodore Rozema, Richard L. Nahin, Jeanne A. Drisko, Kerry L. Lee

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  • ·International longitudinal registry of patients with atrial fibrillation at risk of stroke: Global Anticoagulant Registry in the FIELD (GARFIELD)

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    Ajay K. Kakkar, Iris Mueller, Jean-Pierre Bassand, David A. Fitzmaurice, Samuel Z. Goldhaber, Shinya Goto, Sylvia Haas, Werner Hacke, Gregory Y.H. Lip, Lorenzo G. Mantovani, Freek W.A. Verheugt, Waheed Jamal, Frank Misselwitz, Sophie Rushton-Smith, Alexander G.G. Turpie

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  • ·Responses of mental stress–induced myocardial ischemia to escitalopram treatment: Background, design, and method for the Responses of Mental Stress Induced Myocardial Ischemia to Escitalopram Treatment trial

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    Wei Jiang, Eric J. Velazquez, Zainab Samad, Maragatha Kuchibhatla, Carolyn Martsberger, Joseph Rogers, Redford Williams, Cynthia Kuhn, Thomas L. Ortel, Richard C. Becker, Nicole Pristera, Ranga Krishnan, Christopher M. O'Connor

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  • ·A cardiovascular safety study of LibiGel (testosterone gel) in postmenopausal women with elevated cardiovascular risk and hypoactive sexual desire disorder

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    William B. White, Deborah Grady, Linda C. Giudice, Scott M. Berry, Joanne Zborowski, Michael C. Snabes

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  • ·Single-bolus tenecteplase plus heparin compared with heparin alone for normotensive patients with acute pulmonary embolism who have evidence of right ventricular dysfunction and myocardial injury: Rationale and design of the Pulmonary Embolism Thrombolysis (PEITHO) trial

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    The Steering Committee a ?

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• Results of Expert Meetings

  • ·Eliminating untimely deaths of women from heart disease: Highlights from the Minnesota Women's Heart Summit

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    Ruth Lindquist, Jackie L. Boucher, Elizabeth Zane Grey, Beth Cairns, Shalini Bobra, Denise Windenburg, Suma Konety, Kevin Graham, Russell Luepker, Sharonne N. Hayes

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• Clinical Investigations

  • ·Factors associated with improvement in ejection fraction in clinical practice among patients with heart failure: Findings from IMPROVE HF

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    Jane E. Wilcox, Gregg C. Fonarow, Clyde W. Yancy, Nancy M. Albert, Anne B. Curtis, J. Thomas Heywood, Patches Johnson Inge, Mark L. McBride, Mandeep R. Mehra, Christopher M. O'Connor, Dwight Reynolds, Mary Norine Walsh, Mihai Gheorghiade

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  • ·A proinflammatory monocyte response is associated with myocardial injury and impaired functional outcome in patients with ST-segment elevation myocardial infarction : Monocytes and myocardial infarction

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    Anja M. van der Laan, Alexander Hirsch, Lourens F.H.J. Robbers, Robin Nijveldt, Ingrid Lommerse, Ronak Delewi, Pieter A. van der Vleuten, Bart J. Biemond, Jaap Jan Zwaginga, Wim J. van der Giessen, Felix Zijlstra, Albert C. van Rossum, Carlijn Voermans, C. Ellen van der Schoot, Jan J. Piek

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  • ·Bridging the gender gap: Insights from a contemporary analysis of sex-related differences in the treatment and outcomes of patients with acute coronary syndromes

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    Stephanie Poon, Shaun G. Goodman, Raymond T. Yan, Raffaele Bugiardini, Arlene S. Bierman, Kim A. Eagle, Nina Johnston, Thao Huynh, Francois R. Grondin, Karin Schenck-Gustafsson, Andrew T. Yan

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  • ·Diagnostic accuracy of a point-of-care troponin I assay for acute myocardial infarction within 3 hours after presentation in early presenters to the emergency department with chest pain

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    Deborah B. Diercks, W. Frank Peacock, Judd E. Hollander, Adam J. Singer, Robert Birkhahn, Nathan Shapiro, Ted Glynn, Richard Nowack, Basmah Safdar, Chadwick D. Miller, Elizabeth Lewandrowski, John T. Nagurney

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  • ·Long-term effects of smoking and smoking cessation on exercise stress testing: Three-year outcomes from a randomized clinical trial

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    Asha Asthana, Megan E. Piper, Patrick E. McBride, Ann Ward, Michael C. Fiore, Timothy B. Baker, James H. Stein

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  • ·Relationships between changes in patient-reported health status and functional capacity in outpatients with heart failure

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    Kathryn E. Flynn, Li Lin, Gordon W. Moe, Jonathan G. Howlett, Lawrence J. Fine, John A. Spertus, Timothy R. McConnell, Ileana L. Piña, Kevin P. Weinfurt

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  • ·Nonfatal myocardial infarction and long-term outcomes in coronary artery disease

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    Eric L. Eisenstein, David F. Kong, Patricia A. Cowper, Jay P. Bae, Krishnan Ramaswamy, Kevin J. Anstrom

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  • ·Sex-specific benefits of sirolimus-eluting stent on long-term outcomes in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention: Insights from the Multicenter Evaluation of Single High-Dose Bolus Tirofiban Versus Abciximab With Sirolimus-Eluting Stent or Bare-Metal Stent in Acute Myocardial Infarction Study trial

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    Giuseppe Ferrante, Patrizia Presbitero, Elena Corrada, Gianluca Campo, Leonardo Bolognese, Corrado Vassanelli, Salvatore Colangelo, Nicoletta De Cesare, Alfredo E. Rodriguez, Ezio Bramucci, Raul Moreno, Tommaso Piva, Imad Sheiban, Giampaolo Pasquetto, Francesco Prati, Marco S. Nazzaro, Roberto Ferrari, Marco Valgimigli

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  • ·The role of transthoracic echocardiography in the diagnosis and management of acute type A aortic syndrome

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    Moreno Cecconi, Fabio Chirillo, Carlo Costantini, Gianfranco Iacobone, Ercole Lopez, Raffaele Zanoli, Alberto Gili, Stefano Moretti, Marcello Manfrin, Christopher Münch, Lucia Torracca, Gian Piero Perna

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  • ·Plasma resistin, adiponectin, and risk of incident atrial fibrillation: The Framingham Offspring Study

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    Michiel Rienstra, Jenny X. Sun, Steven A. Lubitz, David S. Frankel, Ramachandran S. Vasan, Daniel Levy, Jared W. Magnani, Lisa M. Sullivan, James B. Meigs, Patrick T. Ellinor, Emelia J. Benjamin

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  • ·Characteristics of sudden arrhythmic death in a diverse, urban community

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    Daniel A. Steinhaus, Eric Vittinghoff, Ellen Moffatt, Amy P. Hart, Philip Ursell, Zian H. Tseng

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• Letters to the Editor

  • ·Bleeding, mortality, and antiplatelet therapy: Results from the Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management, and Avoidance (CHARISMA) trial

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    Saurav Chatterjee, Subhankar Maitra, Anasua Chakraborty

    
  • ·Reply to the letter by Chatterjee et al “Bleeding, mortality, and antiplatelet therapy: Results from the Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management, and Avoidance (CHARISMA) trial”

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    Jeffery S. Berger, Deepak L. Bhatt