Does aging influence clinical presentation and pathological staging in colorectal cancer? - 26/09/15
, R. Medeiros de Almeida b , A.C. Nóbrega dos Santos c , P. Gonçalves de Oliveira b , E. Freitas da Silva d , J. Batista de Sousa b Abstract |
Objective |
To evaluate the influence of age on clinical presentation and pathological staging in colorectal cancer.
Design |
Retrospective chart review.
Setting |
University hospital.
Methods |
The medical records of 216 patients aged ≥50years with colorectal cancer treated between 2006 and 2012 were reviewed. Patients were stratified by age into two groups: 50–64 years and ≥65 years. Clinical presentation and pathological staging were compared between the two groups.
Results |
The older group comprised 116 patients with a mean age of 71.13±4.72years, and the younger group, 100 patients with a mean age of 56.97±4.55. Older and younger adults had similar rates of lower gastrointestinal bleeding (72 vs. 67%, P=0.4389), changes in bowel habit (72 vs. 68%, P=0.5375), and weight loss (55 vs. 53%, P=0.6979). Abdominal pain was less common in the older group (53 vs. 68%, P=0.0028). On multivariate analysis, age did not influence the time elapsed since symptom onset, pathological stage T3/T4, or final pathological stage III/IV.
Conclusion |
Older patients reported a lower frequency of abdominal pain, but time from symptom onset to diagnosis and pathological staging were similar to those of younger patients.
Le texte complet de cet article est disponible en PDF.Keywords : Colorectal cancer, Aging, Older people, Diagnosis, Pathological staging, Clinical presentation
Plan
Vol 6 - N° 5
P. 433-436 - octobre 2015 Retour au numéro
Article précédent
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