Isopropyl alcohol is as efficient as chlorhexidine to prevent contamination of blood cultures - 18/04/17
Abstract |
Background |
False-positive blood cultures can lead to unnecessary risks and misuse of antibiotics; to reduce rates of false-positives, it would be useful to determine whether use of an antiseptic with a prolonged effect is required.
Methods |
Clinical study of efficacy (blinded and randomized) to compare the rate of blood culture contamination when skin antisepsis was performed with 70% isopropyl alcohol or 2% chlorhexidine gluconate in 70% isopropyl alcohol in 2 hospitals. Patients aged 16 years or older with suspected bloodstream infection who were allocated in the emergency room, internal medicine ward, or intensive care unit were included.
Results |
Five of 563 (0.9%) blood cultures from the isopropyl arm and 10 of 539 (1.9%) from the chlorhexidine arm were contaminated. No significant differences were observed among the rate of contamination (χ2 = 1.27; P = .3) or the relative risk of contamination (relative risk = 2.09; 95% confidence interval, 0.72-6.07; P = .2).
Conclusions |
The rates of blood contamination were not different when isopropyl alcohol and chlorhexidine were compared. Isopropyl alcohol could be used for skin antisepsis before blood collection.
Le texte complet de cet article est disponible en PDF.Keywords : Antiseptics, Hemoculture contamination, Anti-infecting agents, Local
Plan
| Conflicts of interest: None to report. |
Vol 45 - N° 4
P. 350-353 - avril 2017 Retour au numéro
Article précédent
- Preoperative bathing of the surgical site with chlorhexidine for infection prevention: Systematic review with meta-analysis
- Lúcia Maciel de Castro Franco, Gláucia Fernandes Cota, Tatiana Saraiva Pinto, Flávia Falci Ercole
- Methodology for analyzing environmental quality indicators in a dynamic operating room environment
- Thomas Gormley, Troy A. Markel, Howard W. Jones, Jennifer Wagner, Damon Greeley, James H. Clarke, Mark Abkowitz, John Ostojic
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?