Glucagon for refractory asthma exacerbation - 19/04/17
Doi : 10.1016/j.ajem.2016.09.063
Jillian M. Cavallari a, b, Tara S. Jawaro a, b, Nadia I. Awad a, ⁎ 
, Patrick J. Bridgeman a, b
, Patrick J. Bridgeman a, b a Department of Pharmacy, Robert Wood Johnson University Hospital, New Brunswick, NJ
b Department of Pharmacy Practice and Administration, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ
⁎Corresponding author at: Emergency Medicine Pharmacist, Robert Wood Johnson University Hospital, 1 Robert Wood Johnson Pl, New Brunswick, NJ 08901.Emergency Medicine PharmacistRobert Wood Johnson University Hospital1 Robert Wood Johnson PlNew BrunswickNJ08901
Abstract |
Glucagon, a hormone secreted by pancreatic alpha cells, causes bronchial smooth muscle relaxation by activating the synthesis of cyclic adenosine monophosphate. It was studied in the 1980s and 1990s as a treatment option for the management of asthma but has since not been evaluated. Data to support its use are limited, but it may serve as a last-line agent for refractory asthma exacerbation. Here we describe 4 cases in which intravenous glucagon was used to manage severe, refractory asthma exacerbation in the emergency department.
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| ☆ | Financial disclosures: The authors have no financial disclosures to report relevant to this manuscript. |
© 2016
Elsevier Inc. Tous droits réservés.
Vol 35 - N° 1
P. 144-145 - janvier 2017 Retour au numéro
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