Successful management of sedation/anesthesia of psittacine species relies on familiarity with their specific anatomy and physiology, and detailed knowledge of the recent advancements in applied pharmacology of the anesthetics and perianesthetic monitoring of cardiovascular and respiratory functions. Each sedation/anesthetic plan should be patient-specific, developed based on preexisting conditions, size, species, age, and estimated risk. Other key factors to improve safety, quality of perioperative care, and client satisfaction are anticipation of complications, extension of close monitoring to the recovery phase, multimodal analgesic approach, stress prevention/reduction, and transparent communication with the owner.