Cardiogenic shock in adults with congenital heart disease: Insights from the FRENSHOCK registry - 12/05/23
, Clément Karsenty 2, Nicolas Lamblin 3, Magalie Ladouceur 4, François Roubille 5, Eric Bonnefoy-Cudraz 6, Etienne Puymirat 7, Edouard Gerbaud 8, Guillaume Leurent 9, Emmanuelle Fillippi 10, Benoît Lattuca 11, Bruno Levy 12, Laurent Bonello 13, Pascal Lim 14, Marie-France Seronde 15, Alain Cariou 16, Xavier Delabranche 17, Nicolas Combaret 18, Clément Delmas 19Résumé |
Introduction |
Data on cardiogenic shock (CS) in adults with congenital heart disease (ACHD) are scarce.
Objective |
We sought to describe CS in ACHD in a nationwide CS registry.
Method |
From the multicentric FRENSHOCK registry (n=772 CS from 49 French centers between April and October 2016), ACHD CS were compared with non-ACHD ones. The primary outcome was defined by all-cause mortality, chronic ventricular assist device (VAD) or heart transplantation at 1-year.
Results |
Out of the 772 patients, 7 (1%) were ACHD. ACHD patients were younger (54 vs. 66years old), with less cardiovascular risk factors, such as hypertension (14.2 vs. 47.5%) and diabetes (14.3 vs. 36.1%), and no ischemic cardiopathy (0 vs. 61.5%). Right heart catheterization (57.1 vs. 15.4%), pacemaker (28.6 vs. 4.6%) and ICD (28.6 vs. 4.8%) were more frequently indicated in the ACHD CS management compared to non-ACHD CS, whereas temporary MCS (0 vs. 7.2%) and invasive mechanical ventilation (14.3 vs. 38.1%) were less likely used in ACHD. At 1-year, primary outcome occurred in 85.7% ACHD and 52.2% non-ACHD (P=0.127) (Fig. 1). Although 1-year mortality was similar (45.4 vs. 42.9% respectively for ACHD and non-ACHD patients, P=1), VAD (14.3 vs. 5.4%, P=0.325), and heart transplantation (28.6 vs. 5.2%, P=0.05) seemed more frequent in ACHD group.
Conclusion |
CS in ACHD is rare accounting for only 1% of an unselected CS population. Despite a younger age and less comorbidities its prognosis remains severe and similar to others patients.
Le texte complet de cet article est disponible en PDF.Plan
Vol 15 - N° 2
P. 223-224 - mai 2023 Retour au numéro
Article précédent
- Antagonizing interleukine-8 improves the durability of biological aortic valves: Translation of fundamental results using a model of subcutaneous aortic valve implantation in rats into clinical application such as cardiac surgery
- Yuthiline Chabry, Kawthar Dhayni, Thierry Caus, Youssef Bennis
- SCN5A variants as genetic arrhythmias triggers for familial bileaflet mitral valve prolapse
- Hager Jaouadi, Alexis Théron, Jérôme Hourdain, Hélène Martel, Karine Nguyen, Raja Habachi, Jean-Claude Deharo, Frédéric Collart, Jean-François Avierinos, Stéphane Zaffran
Bienvenue sur EM-consulte, la référence des professionnels de santé.
L’accès au texte intégral de cet article nécessite un abonnement.
Déjà abonné à cette revue ?