Integrity and filtration efficiency of decontaminated N95/PFF2 masks to protect health care professionals against COVID-19: A systematic literature review and meta-analysis - 19/06/24

, Ana M.M. de Magalhães, PhD b
, Joao L.C. de Oliveira, PhD c
, Angelita P. Costanzi, PhD d
, Carlise R.D. Nora, PhD e
, Denilse D. Trevilato f 
Résumé |
Background |
To evaluate the evidence related to maintaining the integrity and filtration efficiency of N95 and/or PFF2 respirators after decontamination in health care professionals’ protection against COVID-19.
Methods |
Systematic review, developed based on the guidelines from Joanna Briggs Institute for syntheses focusing on effectiveness evidence. The protocol was registered on the International Prospective Register of Ongoing Systematic Reviews platform, under the number CRD42022354256. This study report was developed in accordance with the guidelines recommended by the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Publications between January 2020 and August 2022 were selected of Embase, Medline, CINAHL, Web of Science, Cochrane, SciELO and Virtual Health Library databases. Joanna Briggs critical appraisal tool for nonrandomized experimental tests was used to evaluate the evidence quality.
Results |
Seven articles were included in the data extraction and critical evaluation, and 3 in the meta-analysis. Four studies evaluated the integrity by visual inspection and 2 by electron microscopy. There was no association between the number of cycles increase and the reduction in filtration in up to 10 cycles. None study was considered of high methodological quality.
Conclusions |
There is some evidence that integrity and filtration capacity were maintained after decontamination of N95/PFF2 respirators to prevent COVID-19.
Le texte complet de cet article est disponible en PDF.Highlights |
• | Descontamination of N95 respirators isn't ideal, it is a strategic alternative to mitigate the shortage of PPE during the pandemics. |
• | Different decontamination methods are promising for maintaining the integrity and filtration of N95/PFF2 respirators. |
• | Thre're doubts to the factors that can influence of decontamination, because the N95/PFF2 respirators are to be used one-time only and discarded. |
• | The methods of Steam, VHP, PAF, ETO, HPGP, UV-C are efficient regarding the microorganism's inactivations. |
Key Words : N95 respirators, Personal protective equipment, Systematic review, Sterilization
Plan
| Conflicts of interest: I am sending the manuscript of an article entitled "Integrity and filtration efficiency of decontaminated N95/PFF2 masks for protecting health care workers from COVID-19: systematic review and meta-analysis", which I request be considered for publication in AJIC: American Journal of Infection Control. This is a systematic review with meta-analysis in which we propose to evaluate the evidence related to maintaining integrity and filtration efficiency after decontamination of N95 and/or PFF2 respirators for protecting health care professionals from COVID-19. We, Daniela Silva dos Santos Schneider, Ana Maria Müller de Magalhães, João Lucas Campos de Oliveira, Ana Karina Silva da Rocha Tanaka, authors of the article “Integrity and filtration efficiency of decontaminated N95/PFF2 masks to protect health care professionals against COVID-19: a systematic literature review and meta-analysis”, we declare that this is an original article and that this version, in full or in part, has not been published or is being considered for publication in another journal, whether in printed or electronic format. We declare that the published work is the sole responsibility of the author(s), and AJIC is only responsible for evaluating the work, as a vehicle for scientific publication. AJIC is not responsible for any violations of Copyright Law. We assume full responsibility for the citations and bibliographic references used, as well as the ethical aspects involving study participants. We authorize the use of images and/or speeches for dissemination and advertising purposes, granting all rights reserved to AJIC (ISSN 0196-6533). We declare that there is no conflict of personal, commercial, political, academic, or financial interests and/or affiliations. We confirm that people who contributed to this article, but who do not meet the criteria for authorship, have been mentioned in the acknowledgments. The people or organizations mentioned in the acknowledgments have given written permission for such mention. |
Vol 52 - N° 7
P. 751-758 - juillet 2024 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
