Demystifying delays: Factors associated with timely treatment of adrenocortical carcinoma - 13/12/24
, Julia A. Gasior a, b, Sara P. Ginzberg a, Wajid Amjad a, Amanda Bader a, Jasmine Hwang a, Heather Wachtel a, bAbstract |
Background |
Delays in management of adrenocortical carcinoma (ACC) may lead to worse outcomes. We assessed for delays in ACC treatment according to sociodemographic factors.
Methods |
We performed a retrospective cohort study of patients treated for ACC (2010–2019) utilizing the National Cancer Database. Cox proportional hazards modeling was used to evaluate the associations between sociodemographic, geographic, and clinical factors and time to intervention from diagnosis.
Results |
Across 1399 subjects treated for ACC, the median time to treatment was 27 days (IQR 15–47). Non-Hispanic Black patients (HR 0.798, p = 0.033) and patients aged 40–64 years (HR 0.800, p = 0.008) were at greater risk of delays in care, whereas female patients (HR 1.169, p = 0.011) and those with metastatic disease (HR 1.176, p = 0.010) received more timely care.
Conclusions |
Older age, male sex, and Black race were associated with delays in care for ACC though these delays did not translate to worsened overall survival.
Le texte complet de cet article est disponible en PDF.Highlights |
• | Advanced age, male sex, and Black race were associated with delays in ACC care. |
• | Delays in care, were generally nine days or fewer, however, and did not correspond to worsened overall survival. |
• | The impact of care delays in patients diagnosed surgically could not be quantified. |
Keywords : Adrenocortical carcinoma, ACC, Adrenal, Disparities, Delays in care, Outcomes, Endocrine
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Vol 239
Article 116048- janvier 2025 Retour au numéro
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