Advanced maternal age, short interpregnancy interval, and perinatal outcome - 19/08/11
Reprints: Luc Smits, PhD, Maastricht University, Department of Epidemiology, PO Box 616, Maastricht, Limburg 6200, NetherlandsRésumé |
Objective |
The purpose of this study was to evaluate whether the association between short interpregnancy intervals and perinatal outcome varies with maternal age.
Study Design |
We performed a retrospective cohort study among 263,142 Dutch women with second deliveries that occurred between 2000 and 2007. Outcome variables were preterm delivery (<37 weeks of gestation), low birthweight in term deliveries (<2500 g) and small-for-gestational age (<10th percentile for gestational age on the basis of sex- and parity-specific Dutch standards).
Results |
Short interpregnancy intervals (<6 months) was associated positively with preterm delivery and low birthweight, but not with being small for gestational age. The association of short interpregnancy interval with the risk of preterm delivery was weaker among older than younger women. There was no clear interaction between short interpregnancy interval and maternal age in relation to low birthweight or small for gestational age.
Conclusion |
The results of this study indicate that the association of short interpregnancy interval with preterm delivery attenuates with increasing maternal age.
Le texte complet de cet article est disponible en PDF.Key words : birth interval, interaction, low birthweight, maternal age, small for gestational age
Plan
| Authorship and contribution to the article is limited to the 5 authors indicated. There was no outside funding or technical assistance with the production of this article. |
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| Cite this article as: de Weger FJ, Hukkelhoven CWPM, Serroyen J, et al. Advanced maternal age, short interpregnancy interval, and perinatal outcome. Am J Obstet Gynecol 2011;204:421.e1-9. |
Vol 204 - N° 5
P. 421.e1-421.e9 - mai 2011 Retour au numéro
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