Active Hydrodissection Might Optimize Cryosurgical Ablation of the Prostate - 20/08/11
, Kevin G. Basralian
Reprint requests: Gene S. Rosenberg, M.D., Department of Urology, Hackensack University Medical Center, 20 Prospect Avenue, Suite 719, Hackensack, NJ 07601Résumé |
Objective |
To produce lower temperatures safely in the prostate, and better protect the rectum , as well as maximize the technique of cryosurgical ablation to better eradicate prostate cancer.
Methods |
A total of 10 consecutive patients underwent total, subtotal, or focal cryosurgical ablation, with saline hydrodissection. We found lethal prostate temperatures and safer rectal temperatures. One patient developed a very small rectourethral fistula that healed with catheter drainage alone, prompting a revised technique. The prostate-specific antigen values at short follow-up were very low.
Results |
Temperatures of −10°C to −76°C were achieved outside the prostate at the neurovascular bundle. Post-operative prostate-specific antigen values were 0.10 to 3.4 if total or focal therapy, respectively, was used. A small rectal fistula healed with catheter drainage alone.
Conclusions |
This technique appears to hold great promise and should be investigated further in a larger group of patients with longer follow-up.
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Vol 76 - N° 4
P. 988-991 - octobre 2010 Retour au numéro
Article précédent
- Inverted Ureteral Nipple as Antireflux Technique in Surgical Management of Bilharzial Ureteral Strictures
- Ashraf Abou-Elela, Mohamed Torky, Essam Salah, Ahmad Morsy, Mahmoud Elsherbiny
- Editorial Comment
- Martin Dineen
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