Colored facial cosmetics are designed to add color, blend pigmentation defects, and meet the fashion needs of the individual. Products that fit into this category primarily include facial foundations, but also face powders and blushes. The formulation and use of colored facial cosmetics is an area of dermatology where medicine, science, art, and appearance all intermingle. This makes the study of colored cosmetics challenging and fascinating. Colored cosmetics are of medical significance for their ability to function as camouflaging aids, yet it also is important to recognize dermatoses that rarely may be related to their use. The formulation and efficacy of colored facial cosmetics is grounded firmly in the science of cosmetic chemistry and skin physiology. Colored cosmetics are valued for their appearance-enhancing capability and the intangible aspects of well-being that their use imparts. This article discusses the art and science of colored cosmetics to provide a fund of knowledge useful to the physician in tackling problems related to appearance and dermatologic disease.