Environmental variables as potential modifiable risk factors of preterm birth in Philadelphia, PA - 28/01/15
, Mary D. Sammel, ScD b, Tara D. Jackson, PhD c, Meghan E. Ryan, BA a, Meghan A. McShea, BS a, Michal A. Elovitz, MD aAbstract |
Objective |
To examine whether variation in neighborhood context is associated with preterm birth (PTB) outcomes and gestational age (GA) at delivery in Philadelphia, and to determine whether these associations might persist when considering relevant individual-level variables.
Study Design |
We analyzed individual-level data collected for a prospective cohort study of singleton pregnancies with preterm labor. We merged block-group level data to each individual's home address. Unadjusted analyses were performed to determine the association between block-group variables and individual-level outcomes. Block-group variables identified as potential risk factors were incorporated into multivariable individual-level models to determine significance.
Results |
We analyzed data for 817 women. The prevalence of PTB <37 weeks was 41.5%. Although in unadjusted analyses several block-group variables were associated with PTB and GA at delivery, none retained significance in individual-level multivariable models.
Conclusion |
Block-group level data were not associated with PTB outcomes or GA at delivery in Philadelphia.
Le texte complet de cet article est disponible en PDF.Key words : census block-group, environment, Philadelphia, preterm birth
Plan
| The authors report no conflict of interest. |
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| The material herein represents the research and conclusions of the authors and does not necessarily reflect the views of the Eunice Kennedy Shriver National Institute of Child Health and Human Development. |
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| Financial support for this project was provided by March of Dimes grant number 21-FY08-539 (principal investigator: Elovitz). Drs Bastek and Sammel were supported by grant number K12HD001265 (principal investigator: Driscoll; Scholar: Bastek) from the Eunice Kennedy Shriver National Institute of Child Health and Human Development . |
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| Cite this article as: Bastek JA, Sammel MD, Jackson TD, et al. Environmental variables as potential modifiable risk factors of preterm birth in Philadelphia, PA. Am J Obstet Gynecol 2015;212:236.e1-10. |
Vol 212 - N° 2
P. 236.e1-236.e10 - février 2015 Retour au numéro
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