Postoperative pyoderma gangrenosum (PG): The Mayo Clinic experience of 20 years from 1994 through 2014 - 14/09/15
Abstract |
Background |
Postoperative pyoderma gangrenosum (PG) is a neutrophilic dermatosis characterized by the development of PG-type lesions within surgical sites.
Objective |
We sought to characterize postoperative PG as a distinct subtype of PG for earlier recognition and prevention of improper therapy.
Methods |
We conducted a retrospective chart review of patients with nonperistomal postoperative PG at Mayo Clinic from 1994 to 2014.x
Results |
Eighteen patients had postoperative PG with an average age of 58 years. Fifteen (83%) were female. Among patients with postoperative PG, 4 (22%) had an associated systemic disease traditionally associated with PG. Sites of postoperative PG included 7 breast (38%), 7 abdomen (38%), 1 back, 1 shoulder, 1 ankle, and 1 scrotum, witxxh breast reconstruction being the most common surgery. The average time to symptoms was 11 days. No patients had a fever. Eight (44%) had documented anemia and 5 (27%) had leukocytosis. Antibiotics and systemic corticosteroids were initiated in 10 (56%) and 14 (83%), respectively. Debridement was done in 11 (61%) patients.
Limitations |
Small sample size and retrospective study are limitations.
Conclusion |
Postoperative PG is a rare surgical complication with predilection for the breast and abdomen of females and has less association with systemic disease than idiopathic PG. Early recognition may prevent unnecessary debridements and morbidity.
Il testo completo di questo articolo è disponibile in PDF.Key words : breast, Cullen gangrene, dehiscence, dermatitis ulcerosa, neutrophilic dermatosis, postoperative, postsurgical, pyoderma gangrenosum, wound infection
Abbreviations used : IBD, IL, PG, PMN, RA
Mappa
| Funding sources: None. |
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| Conflicts of interest: None declared. |
Vol 73 - N° 4
P. 615-622 - ottobre 2015 Ritorno al numero
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