Ischemic Conditioning: Implications for Emergency Medicine - 25/08/16
Doi : 10.1016/j.annemergmed.2016.02.020
Kenneth Frumkin, MD, PhD ⁎ 
, Adam S. Bloom, LT, MC, USN
, Adam S. Bloom, LT, MC, USN Emergency Medicine Department, Naval Medical Center, Portsmouth, VA
∗Corresponding Author.
Abstract |
Ischemic conditioning refers to the ability of brief episodes of controlled hypoperfusion around the time of an acute ischemic event to protect the target organ from reperfusion injury. A considerable body of literature suggests that interventions as simple and safe as repetitively inflating a blood pressure cuff could reduce the size and long-term morbidity of myocardial and cerebral infarction. This review introduces and summarizes the body of evidence contributing to these impressions.
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| Supervising editor: Donald M. Yealy, MD |
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| Author contributions: KF conceived of the review and edited the manuscript. ASB and KF reviewed and synthesized separate portions of the literature and contributed to the primary drafts. |
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| Funding and support: By Annals policy, all authors are required to disclose any and all commercial, financial, and other relationships in any way related to the subject of this article as per ICMJE conflict of interest guidelines (see www.icmje.org/). The authors have stated that no such relationships exist. |
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| The views expressed in this article are those of the authors and do not necessarily reflect the official policy or position of the Department of the Navy, Department of Defense, or the United States government. Both authors are an employee of the US government and a military service member. This work was prepared as part of their official duties. Title 17 U.S.C. 105 provides that “Copyright protection under this title is not available for any work of the United States Government.” Title 17 U.S.C. 101 defines a US government work as a work prepared by a military service member or employee of the US government as part of that person’s official duties. |
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| A podcast for this article is available at www.annemergmed.com. |
© 2016
Pubblicato da Elsevier Masson SAS.
Vol 68 - N° 3
P. 268-274 - settembre 2016 Ritorno al numero
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