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Abdominal Wall Reconstruction with Concomitant Ostomy-Associated Hernia Repair: Outcomes and Propensity Score Analysis - 19/04/17

Doi : 10.1016/j.jamcollsurg.2016.11.013 
Alexander F. Mericli, MD, Patrick B. Garvey, MD, FACS, Salvatore Giordano, MD, PhD, Jun Liu, PhD, Donald P. Baumann, MD, FACS, Charles E. Butler, MD, FACS ⁎
 Department of Plastic Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX 

∗Correspondence address: Charles E Butler, MD, FACS, Department of Plastic Surgery, The University of Texas MD Anderson Cancer Center, 1400 Pressler St, Unit 1488, Houston, TX 77030.Department of Plastic SurgeryThe University of Texas MD Anderson Cancer Center1400 Pressler StUnit 1488HoustonTX77030

Abstract

Background

The optimal strategy for abdominal wall reconstruction in the presence of a stomal-site hernia is unclear. We hypothesized that the rate of ventral hernia recurrence in patients undergoing a combined ventral hernia repair and stomal-site herniorraphy would not differ clinically from the ventral hernia recurrence rate in patients undergoing an isolated ventral hernia repair. We also hypothesized that bridged ventral hernia repairs result in worse outcomes compared with reinforced repairs, regardless of stomal hernia.

Study Design

We retrospectively reviewed prospectively collected data from consecutive abdominal wall reconstructions performed with acellular dermal matrix (ADM) at a single center between 2000 and 2015. We compared patients who underwent a ventral hernia repair alone (AWR) and those who underwent both a ventral hernia repair and ostomy-associated herniorraphy (AWR+O). We conducted a propensity score matched analysis to compare the outcomes between the 2 groups. Multivariable Cox proportional hazards and logistic regression models were used to study associations between potential predictive or protective reconstructive strategies and surgical outcomes.

Results

We included 499 patients (median follow-up 27.2 months; interquartile range [IQR] 12.4 to 46.6 months), 118 AWR+O and 381 AWR. After propensity score matching, 91 pairs were obtained. Ventral hernia recurrence was not statistically associated with ostomy-associated herniorraphy (adjusted hazard ratio [HR] 0.7; 95% CI 0.3 to 1.5; p = 0.34). However, the AWR+O group experienced a significantly higher percentage of surgical site occurrences (34.1%) than the AWR group (18.7%; adjusted odds ratio 2.3; 95% CI 1.4 to 3.7; p < 0.001). In the AWR group, there were significantly fewer ventral hernia recurrences when the repair was reinforced compared with bridged (5.3% vs 38.5%; p < 0.001).

Conclusions

There was no statistically significant difference in ventral hernia recurrence between the AWR and AWR+O groups. Bridging was associated with an increased rate of hernia recurrence and should be avoided if possible.

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Abbreviations and Acronyms : ADM, ASA, AWR, AWR+O, IQR, SSI, SSO, VHWG


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 Disclosure Information: Dr Mericli received support from Acelity for travel to the European Association of Plastic Surgeons' annual meeting to present this paper. All other authors have nothing to disclose.
 Support: This work was supported in part by the NIH/NCI under award number P30CA016672 and used the Clinical Trials Support Resource.


© 2016  American College of Surgeons. Pubblicato da Elsevier Masson SAS. Tutti i diritti riservati.
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Vol 224 - N° 3

P. 351 - marzo 2017 Ritorno al numero
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  • Long-Term Outcomes after Abdominal Wall Reconstruction with Acellular Dermal Matrix
  • Patrick B. Garvey, Salvatore A. Giordano, Donald P. Baumann, Jun Liu, Charles E. Butler
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