Detecting Pharmaceuticals in the Red Blood Cell Inventory of a Hospital Blood Bank - 23/09/17
Doi : 10.1016/j.jpeds.2017.06.010
Eric A. Gehrie, MD 1, Amaris Keiser, MD 2, Carrie J. Haglock-Adler, MS 3, Frederick Strathmann, PhD 4, Garrett S. Booth, MD 1, * 
1 Department of Pathology, Johns Hopkins University, Baltimore, MD
2 Department of Pediatrics, Johns Hopkins University, Baltimore, MD
3 Agilent Technologies, Santa Clara, CA
4 NMS Labs, Willow Grove, PA
*Reprint requests: Garrett S. Booth, MD, Vanderbilt University Medical Center, 1301 Medical Center Drive TVC 4650H, Nashville, TN 37232.Vanderbilt University Medical Center1301 Medical Center Drive TVC 4650HNashvilleTN37232
Abstract |
We tested 220 red blood cell units for the presence of pharmaceuticals; 15 units (6.8%) were confirmed to contain low concentrations of opiates, benzodiazepines, stimulants, or barbiturates. Further study is needed to determine whether these drugs, which are not prohibited in donated blood by current Food and Drug Administration standards, could mediate adverse reactions in children.
Il testo completo di questo articolo è disponibile in PDF.Keywords : blood, transfusion, pediatrics, drugs, contamination
Abbreviations : FDA, RBC, TOF
Mappa
| Supported in part by Vanderbilt University Medical Center CTSA Grant # UL1 RR024975-01 from NCRR/NIH. The authors declare no conflicts of interest. |
© 2017
Elsevier Inc. Tutti i diritti riservati.
Vol 189
P. 227 - ottobre 2017 Ritorno al numero
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