Big data-driven precision medicine: Starting the custom-made era of iatrology - 28/08/20
, Hui Luo a, ⁎ , Xiao Zhu a, ⁎ Benvenuto su EM|consulte, il riferimento dei professionisti della salute.
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Highlights |
• | Precision medicine is driven by omics and big data. |
• | Precision medicine is widely used in various kinds of diseases. |
• | Precision medicine still has some limitations, but it has a bright future. |
Abstract |
Precision medicine is a new therapeutic concept and method emerging in recent years. The rapid development of precision medicine is driven by the development of omics related technology, biological information and big data science. Precision medicine is provided to implement precise and personalized treatment for diseases and specific patients. Precision medicine is commonly used in the diagnosis, treatment and prevention of various diseases. This review introduces the application of precision medicine in eight systematic diseases of the human body, and systematically presenting the current situation of precision medicine. At the same time, the shortcomings and limitations of precision medicine are pointed out. Finally, we prospect the development of precision medicine.
Il testo completo di questo articolo è disponibile in PDF.Abbreviations : ATB, AIN, AKI, ACAT2, ARPC5, AD, AKT, BMP-2, BMP-2n, BMI, BRCA2, BET, BRD2, BRD3, BRD4, CRISPR, CRP, Copd, CKD, Cys, CLUS, CEMIP, cHCC-CC, ctDNA, CD24, CLU, CTNNB1, DKK3, DPP-4, DNA, DJ-1, DHCR24, eRNA, EGFR, ER, ESR1, ERBB2, FDA, FOXO3, FCN2, FDFT1, GAD, Hcy, HA, HbA1C, HOMA-β, HOMA-IR, HCV, HIV, HAUSP, HER-2, IPF, IgA, IL-9, IBD, IBD1, IBD2, IPO11, KL-6, KDR, LP-PLA2, LTB, LRRK2, MMP-2, MAIT, miRNA, mTOR, MALAT-1, MIF, MMP1, mNGS, MUC1, MAPT, Nanopro 1000, NAFLD, NGS, NSCLC, OS, PIGR, POF, PARP, PARP1, PD-1, PCGEM1, PLA2G7, PARK7, PGR, PDCD1, RNA-seq, ROS, ROS1, RAGE-Seq, RAC1, Smurf1, Smurf1e, SP-D, SERD, SFTPD, SNCA, SPOP, TB, T1D, T2DM, TNA, ThyroSeq, Usp7, VEGFR2, YAP, YAP1, YKi
Keywords : Precision medicine, Omics, Sequencing, Medical big data, Biomarker
Mappa
Vol 129
Articolo 110445- settembre 2020 Ritorno al numero
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