A novel predictive tool for prognosis in elderly patients with urinary tract infection: Modified PRACTICE - 25/11/20

, Sung Uk Cho, MD, Yeonho You, MD, PhD, Jung Soo Park, MD, PhD, Jin Hong Min, MD, PhD, Wonjoon Jeong, MD, Yong Chul Cho, MD, Hong Joon Ahn, MD, Changshin Kang, MDAbstract |
Purpose |
We evaluated whether combining the serum albumin level and the Prediction Rule for Admission policy in Complicated urinary Tract InfeCtion LEiden (PRACTICE) class could be a prognostic predictor in elderly patients with urinary tract infection (UTI).
Methods |
We retrospectively included adult patients (age ≥ 65 years) with UTI who were hospitalized in the emergency department (ED) between January 1, 2014 and December 31, 2018. We graded the serum albumin level and classified the PRACTICE score; the modified PRACTICE was defined as the sum of the albumin level grade and the PRACTICE class. We comparatively assessed the predictive value for in-hospital mortality and admission to the intensive care unit (ICU) in survivor and non-survivor groups.
Results |
In total, the study analysis included 1159 patients, and in-hospital mortality was 3.4% (n = 39). The modified PRACTICE score (4.0 [1.4] vs 6.1 [1.2], p < 0.001) was significantly increased in the non-survivor group. The area under the curve value of factors associated with in-hospital mortality were the Modified Early Warning Score (MEWS) 0.57 (95% CI 0.54–0.60), albumin 0.83 (95% CI 0.81–0.85), PRACTICE 0.71 (95% CI 0.69–0.74), and the modified PRACTICE 0.86 (95% CI 0.84–0.88). Factors associated with ICU admission were MEWS 0.65 (95% CI 0.62–0.68), albumin 0.66 (95% CI 0.64–0.69), PRACTICE 0.66 (95% CI 0.63–0.68), and the modified PRACTICE 0.72 (95% CI 0.69–0.74).
Conclusion |
The modified PRACTICE score can be a useful prognostic predictor in elderly patients with UTI.
Il testo completo di questo articolo è disponibile in PDF.Keywords : Urinary tract infection, Albumin, Prognosis, Mortality
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Vol 38 - N° 10
P. 2002-2006 - ottobre 2020 Ritorno al numeroBenvenuto su EM|consulte, il riferimento dei professionisti della salute.
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