AsthmaMap: An interactive knowledge repository for mechanisms of asthma - 04/03/21
Doi : 10.1016/j.jaci.2020.11.032
Alexander Mazein, PhD a, b, c, ⁎ 
, Olga Ivanova, MSc a, d, e, Irina Balaur, PhD a, Marek Ostaszewski, PhD c, Valeriya Berzhitskaya, PhD f, Tatiana Serebriyskaya, PhD f, Thomas Ligon, PhD g, Jan Hasenauer, PhD h, i, Bertrand De Meulder, PhD a, Rupert W. Overall, PhD j, k, Ludovic Roy, MSc a, Richard G. Knowles, PhD l, Craig E. Wheelock, PhD m, Sven-Erik Dahlen, MD, PhD n, Kian Fan Chung, MD o, Ian M. Adcock, PhD o, Graham Roberts, DM p, q, Ratko Djukanovic, MD r, s, Johann Pellet, MSc a, Piotr Gawron, PhD c, Rudi Balling, PhD c, Anke H. Maitland-van der Zee, PharmD, PhD e, Reinhard Schneider, PhD c, Peter J. Sterk, MD e, Charles Auffray, PhD a
the
, Olga Ivanova, MSc a, d, e, Irina Balaur, PhD a, Marek Ostaszewski, PhD c, Valeriya Berzhitskaya, PhD f, Tatiana Serebriyskaya, PhD f, Thomas Ligon, PhD g, Jan Hasenauer, PhD h, i, Bertrand De Meulder, PhD a, Rupert W. Overall, PhD j, k, Ludovic Roy, MSc a, Richard G. Knowles, PhD l, Craig E. Wheelock, PhD m, Sven-Erik Dahlen, MD, PhD n, Kian Fan Chung, MD o, Ian M. Adcock, PhD o, Graham Roberts, DM p, q, Ratko Djukanovic, MD r, s, Johann Pellet, MSc a, Piotr Gawron, PhD c, Rudi Balling, PhD c, Anke H. Maitland-van der Zee, PharmD, PhD e, Reinhard Schneider, PhD c, Peter J. Sterk, MD e, Charles Auffray, PhD athe
U-BIOPRED Study Group,
theeTRIKS Consortium
a European Institute for Systems Biology and Medicine, Université de Lyon, Lyon, France
b Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow, Russia
c Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Belvaux, Luxembourg
d Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
e Respiratory Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands
f Moscow Institute of Physics and Technology, Dolgoprudny, Moscow, Russia
g Faculty of Physics and Center for NanoScience (CeNS), Ludwig-Maximilians-Universität, Munich, Germany
h Institute of Computational Biology, Helmholtz Zentrum München, Neuherberg, Germany
i Faculty of Mathematics and Natural Sciences, University of Bonn, Endenicher, Bonn, Germany
j Center for Regenerative Therapies Dresden (CRTD), Technische Universität Dresden, Dresden, Germany
k German Center for Neurodegenerative Diseases (DZNE) Dresden, Dresden, Germany
l Knowles Consulting, Stevenage Bioscience Catalyst, Stevenage, United Kingdom
m Division of Physiological Chemistry 2, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden
n Unit for Experimental Asthma and Allergy Research, Institute of Environmental Medicine (IMM), Karolinska Institutet, Solna, Sweden
o National Heart & Lung Institute, Imperial College London, London, United Kingdom
p Clinical and Experimental Sciences and Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
q NIHR Southampton Biomedical Research Centre, Southampton, United Kingdom
r Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, University of Southampton, Southampton, United Kingdom
s NIHR Southampton Respiratory Biomedical Research Unit, Southampton University Hospital, Southampton, United Kingdom
∗Corresponding author: Alexander Mazein, PhD, Luxembourg Centre for Systems Biomedicine, University of Luxembourg, 6 Avenue du Swing, L-4367 Belvaux, Luxembourg.Luxembourg Centre for Systems BiomedicineUniversity of Luxembourg6 Avenue du SwingBelvauxLuxembourgL-4367
Key words : Asthma, disease mechanisms, disease map, knowledge representation, data interpretation
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Mappa
| Disclosure of potential conflict of interest: S.-E. Dahlen reports personal fees from AstraZeneca, Boehringer-Ingelheim, Cayman Chemicals, GlaxoSmithKline (GSK), Novartis, Regeneron, Roche, Sanofi, and Teva outside the submitted work. K. F. Chung has received honoraria for participating in advisory board meetings of GSK, AstraZeneca, Roche, Novartis, Merck, BI, TEVA, and Shionogi regarding treatments for asthma, chronic obstructive pulmonary disease, and chronic cough and has also been remunerated for speaking engagements. R. Balling is a founder and a shareholder of MEGENO S.A. and a shareholder of ITTM S.A. R. Djukanovic reports receiving fees for lectures at symposia organized by Novartis, AstraZeneca, and TEVA; consultation for TEVA and Novartis as member of advisory boards; participation in a scientific discussion about asthma organized by GSK; and is a cofounder and current consultant and has shares in Synairgen, a University of Southampton spin-out company. A. H. Maitland-van der Zee reports grants and personal fees from Boehringer Ingelheim and GSK, grants from Vertex, and personal fees from AstraZeneca, all paid to her institution, and, in a public-private partnership, sponsored by Health Holland matching grants from Boehringer Ingelheim, Breathomix, Fluidda, Ortec Logiqcare, Philips, Quantib-U, Smartfish, SODAQ, Thirona, TopMD, and Novartis outside the submitted work. R. Schneider is a founder and a shareholder of MEGENO S.A. and ITTM S.A. P. J. Sterk is a scientific adviser and officially has a nonsubstantial interest in the start-up company Breathomix BV, which produces eNoses and accompanying cloud algorithms. The rest of the authors declare that they have no relevant conflicts of interest. |
© 2020
American Academy of Allergy, Asthma & Immunology. Tutti i diritti riservati.
Vol 147 - N° 3
P. 853-856 - marzo 2021 Ritorno al numero
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