Impaired diffusing capacity for carbon monoxide is common in critically ill Covid-19 patients at four months post-discharge - 11/05/21
, Frithiof R b, ⁎, Emilsson Öi a, Larson IM b, Lipcsey M b, c, Rubertsson S b, Wallin E b, Janson C a, Hultström M b, d, 1, Malinovschi A e, 1
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Abstract |
There is limited knowledge about the long-term effects on pulmonary function of COVID-19 in patients that required intensive care treatment. Spirometry and diffusing capacity for carbon monoxide (DLCO) were measured in 60 subjects at 3-6 months post discharge. Impaired lung function was found in 52% of the subjects, with reduced DLCO as the main finding. The risk increased with age above 60 years, need for mechanical ventilation and longer ICU stay as well as lower levels of C-reactive protein at admission. This suggests the need of follow-up with pulmonary function testing in intensive-care treated patients.
Il testo completo di questo articolo è disponibile in PDF.Highlights |
• | Four months after Covid −19 over half of those treated in ICU have impaired lung function. |
• | The most common impairment is reduced diffusing capacity, present in 45%. |
• | This risk increases with age above 60, need for mechanical ventilation and time in ICU. |
• | CRP at admission and as nadir lympho- and leukocytes was lower in the affected group. |
Keywords : COVID-19, Follow up, Lung function, ARDS, Diffusion capacity, ICU treatment
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Vol 182
Articolo 106394- giugno 2021 Ritorno al numero
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