Interaction between non-coding RNAs and Toll-like receptors - 17/06/21
, Majid Mokhtari h, ⁎ 
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Abstract |
Toll-like receptors (TLRs) are a large group of pattern recognition receptors which are involved in the regulation of innate immune responses. Based on the interplay between TLRs and adapter molecules, two distinctive signaling cascades, namely the MyD88-dependent and TRIF-dependent pathways have been recognized. TLRs are involved in the development of a wide variety of diseases including cancer and autoimmune disorders. A large body of evidence has shown interaction between two classes of non-coding RNAs, namely microRNAs (miRNAs) and long noncoding RNAs (lncRNAs). These interactions have prominent roles in the pathogenesis of several disorders including infectious disorders, autoimmune conditions and neoplastic disorders. This review aims at description of the interaction between these non-coding RNAs and TLRs.
Il testo completo di questo articolo è disponibile in PDF.Keywords : Non-coding RNA, MiRNA, LncRNA, TLR, Toll-like receptor
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Vol 140
Articolo 111784- agosto 2021 Ritorno al numeroBenvenuto su EM|consulte, il riferimento dei professionisti della salute.
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