A personalized approach to non-invasive ventilation masks in amyotrophic lateral sclerosis using facial scanning and 3D-printing - 06/12/21

Doi : 10.1016/j.stlm.2021.100027

Stephen A. Goutman ^a,^⁎ , Lei Chen ^b,^c , Jeffrey S. Plott ^b,^d,^e , Kyle K. Vankoevering ^d,^f,^g , Armando Kurili ^h , Albert J. Shih ^b , Glenn E. Green ^f
^a University of Michigan Department of Neurology, Ann Arbor, MI, USA
^b Univeristy of Michigan, Department of Mechanical Engineering, Ann Arbor, MI, USA
^c University of Massachusetts Lowell, Department of Mechanical Engineering, Lowell, MA, USA
^d Univeristy of Michigan, Department of Biomedical Engineering, Ann Arbor, MI, USA
^e Univeristy of Michigan, Department of Surgery, Ann Arbor, MI, USA
^f University of Michigan, Department of Otolaryngology, Ann Arbor, MI, USA
^g Ohio State University, Department of Otolaryngology, Columbus, OH, USA
^h University of Michigan, Division of Pulmonary & Critical Care Medicine, Ann Arbor, MI, USA

^⁎Corresponding author at: Department of Neurology, 1500 E Medical Center Dr, Ann Arbor, MI, 48109-5223, USA.Department of Neurology1500 E Medical Center DrAnn ArborMI48109-5223USA

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Abstract

We fabricated personalized non-invasive ventilation (NIV) mask interfaces for amyotrophic lateral sclerosis (ALS) participants. A NIV cushion design was fit to a contact profile from the participant's topographic facial model obtained from a 3D scanner then converted to a mold that was 3D-printed and subsequently cast with medical grade silicone and affixed to a mask frame. 3D scanner resolution plays an important role in mask interface fabrication, particularly around the nose, and iterative design changes may be needed. This may be an important new strategy to increase use of NIV for persons with ALS; further study is encouraged.

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Keywords : 3d printing, Non-invasive ventilation, Amyotrophic lateral sclerosis, Personalized medicine