Simplified robot-assisted endoscopic submucosal dissection for esophageal and gastric lesions: a randomized controlled porcine study (with videos) - 14/06/22
Abstract |
Background and Aims |
Effective countertraction is a main challenging issue in endoscopic submucosal dissection (ESD). Several countertraction methods have been developed to address this issue. The aim of this study was to compare the efficacy of ESD using a novel simplified robot, the flexible auxiliary single-arm transluminal endoscopic robot (FASTER), with a traditional technique.
Methods |
This was a prospective, randomized animal study. Forty-eight ESDs in 6 pigs were carried out at 8 different locations (gastric antrum, gastric body, lower esophagus, and middle esophagus) by the conventional method (n = 24) and by the FASTER-assisted method (n = 24). The primary outcomes were total procedure time, dissection time, and rate of direct-vision dissection. Secondary endpoints were completeness of en-bloc resection and adverse event rate.
Results |
The total procedure time was significantly shorter in FASTER-assisted ESD than in conventional ESD (18.8 vs 32.8 minutes; P < .001). In contrast to the median direct-vision dissection rate of 73% with conventional ESD, the FASTER-assisted group had a significantly higher rate of 96% (P < .001). The number of sites of muscular damage was significantly lower using the FASTER-assisted method than the conventional method (6 vs 21, respectively; P = .018). This improvement was more apparent in esophageal lesions compared with gastric lesions.
Conclusions |
This study demonstrated that using a simplified robot during ESD is technically feasible and enables the endoscopist to dynamically use countertraction. This device could significantly reduce procedure time compared with conventional ESD techniques.
Il testo completo di questo articolo è disponibile in PDF.Abbreviations : ESD, FASTER, IQR
Mappa
| DISCLOSURE: All authors disclosed no financial relationships. Research support for this study was provided by the National Key R&D Program of China (2018YFB1307700),Natural Science Foundation of Shandong Province, China (ZR2020LZL003),Key Research and Development Program of Shandong Province(2018CXGC1209), and Taishan Scholars Program of Shandong Province and National Clinical Research Center for Digestive Diseases supporting technology project (2015BAI13B07). |
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| DIVERSITY, EQUITY, AND INCLUSION: We worked to ensure sex balance in the selection of nonhuman subjects. The author list of this article includes contributors from the location where the research was conducted who participated in the data collection, design, analysis, and/or interpretation of the work. |
Vol 96 - N° 1
P. 140-147 - luglio 2022 Ritorno al numeroBenvenuto su EM|consulte, il riferimento dei professionisti della salute.
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