Cutaneous Mesenchymal Sarcomas - 18/11/22

Doi : 10.1016/j.det.2022.07.011

Frances Walocko, MD ^a, Rachel E. Christensen, BS ^a, Brandon Worley, MD ^b, Murad Alam, MD, MBA, MSCI ^a,^c,^d,^e,^⁎
^a Department of Dermatology, Feinberg School of Medicine, Northwestern University, 676 North Saint Clair Street, 1600, Chicago, IL 60611, USA
^b Florida Dermatology and Skin Cancer Centers, 421 Linden Lane, Lake Wales, Lake Wales, FL 33853, USA
^c Department of Surgery, Feinberg School of Medicine, Northwestern University, 676 North Saint Clair Street, 1600, Chicago, IL 60611, USA
^d Department of Otolaryngology, Feinberg School of Medicine, Northwestern University, 676 North Saint Clair Street, 1600, Chicago, IL 60611, USA
^e Department of Medical Social Sciences, Feinberg School of Medicine, Northwestern University, 676 North Saint Clair Street, 1600, Chicago, IL 60611, USA

^∗Corresponding author. Department of Dermatology, Feinberg School of Medicine, Northwestern University, 676 North Saint Clair Street, 1600, Chicago, IL 60611.Department of DermatologyFeinberg School of MedicineNorthwestern University676 North Saint Clair Street, 1600ChicagoIL60611

Riassunto

Cutaneous mesenchymal sarcomas are rare malignancies that include dermatofibrosarcoma protuberans, atypical fibroxanthoma, pleomorphic dermal sarcoma, cutaneous angiosarcoma, myofibrosarcoma, and leiomyosarcoma. These tumors lack consensus guidelines on staging and management. Treatment of local disease involves complete surgical removal but recurrence rates are higher compared with more common forms of nonmelanoma skin cancer. Cutaneous angiosarcoma, pleomorphic dermal sarcoma, and subcutaneous leiomyosarcoma have increased risk of metastatic spread and lower survival rate. Further research is needed on targeted therapies for these more aggressive sarcomas.

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Keywords : Cutaneous mesenchymal sarcoma, Mohs micrographic surgery, Nonmelanoma skin cancer, Dermatologic surgery

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Key points

Introduction

Discussion

Dermatofibrosarcoma Protuberans

Atypical Fibroxanthoma/Pleomorphic Dermal Sarcoma

Cutaneous Angiosarcoma

Esportazione

Vol 41 - N° 1

P. 133-140 - gennaio 2023 Ritorno al numero

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Adnexal and Sebaceous Carcinomas
Edward W. Seger, Brett C. Neill, Stanislav N. Tolkachjov

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Cutaneous Mesenchymal Sarcomas - 18/11/22

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