Lymph node retrieval colon cancer: Are we making the grade? - 30/08/23
Abstract |
Background |
Adequate lymph node (LN) excision is imperative for pathologic staging and determination of adjuvant treatment.
Methods |
he 2004–2017 National Cancer Database (NCDB) was queried for curative colon cancer resections. Tumors were categorized by location: left, right, and transverse colon cancers. Adequate (12–20 LNs) vs. inadequate (<12 LNs) lymphadenectomy was examined and sub-analysis of <12 LNs, 12–20 LNs or >20 LNs. Primary outcome was predictors of inadequate lymph node retrieval.
Results |
Of 101,551 patients, 11.2% (11,439) had inadequate lymphadenectomy. The inadequate lymphadenectomy rate steadily decreased. On multivariable analysis, inadequate LN retrieval was associated with transverse (OR 1.49, CI [1.30–1.71]) and left colon cancers (OR 2.66, CI [2.42–2.93], whereas income >$63,333 had decreased likelihood of inadequate LN retrieval (OR 0.68, CI[0.56–0.82].
Conclusion |
We are making the grade as NCDB data demonstrates a steady decrease in inadequate lymphadenectomy (2004–2017). There remain socioeconomic risk factors for inadequate lymphadenectomy that need to be addressed.
Il testo completo di questo articolo è disponibile in PDF.Graphical abstract |
Highlights |
• | Adequate lymphadenectomy for colon cancer resections has steadily increased. |
• | Patients with >20 lymph nodes retrieved had optimal 5 year overall survival. |
• | There are socioeconomic variables that predict inadequate lymph node retrieval. |
Keywords : Lymphadenectomy, Colon cancer, NCDB
Mappa
Vol 226 - N° 4
P. 477-484 - ottobre 2023 Ritorno al numero
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