Breakthroughs in understanding and treating eosinophilic gastrointestinal diseases presented at the CEGIR/TIGERs Symposium at the 2022 American Academy of Allergy, Asthma & Immunology Meeting - 07/12/23
Doi : 10.1016/j.jaci.2023.08.021
Mirna Chehade, MD, MPH a, ⁎ 
, Benjamin L. Wright, MD b, c, Dan Atkins, MD d, Seema S. Aceves, MD, PhD e, f, Steven J. Ackerman, PhD g, Amal H. Assa’ad, MD h, Maureen Bauer, MD d, Margaret H. Collins, MD h, Scott P. Commins, MD, PhD i, Carla M. Davis, MD j, k, Evan S. Dellon, MD l, Bethan Doerfler, RDN m, Gerald J. Gleich, MD n, Sandeep K. Gupta, MD, PhD o, David A. Hill, MD, PhD p, q, Elizabeth T. Jensen, PhD r, David Katzka, MD s, Kara Kliewer, PhD h, Ellyn Kodroff t, Leah C. Kottyan, PhD u, Shay Kyle t, Amanda B. Muir, MD p, q, Robert D. Pesek, MD v, w, Kathryn Peterson, MD x, Wayne G. Shreffler, MD, PhD y, z, aa, Jonathan M. Spergel, MD, PhD p, q, Mary Jo Strobel bb, Joshua Wechsler, MD cc, Nives Zimmermann, MD h, Glenn T. Furuta, MD d, Marc E. Rothenberg, MD, PhD h
, Benjamin L. Wright, MD b, c, Dan Atkins, MD d, Seema S. Aceves, MD, PhD e, f, Steven J. Ackerman, PhD g, Amal H. Assa’ad, MD h, Maureen Bauer, MD d, Margaret H. Collins, MD h, Scott P. Commins, MD, PhD i, Carla M. Davis, MD j, k, Evan S. Dellon, MD l, Bethan Doerfler, RDN m, Gerald J. Gleich, MD n, Sandeep K. Gupta, MD, PhD o, David A. Hill, MD, PhD p, q, Elizabeth T. Jensen, PhD r, David Katzka, MD s, Kara Kliewer, PhD h, Ellyn Kodroff t, Leah C. Kottyan, PhD u, Shay Kyle t, Amanda B. Muir, MD p, q, Robert D. Pesek, MD v, w, Kathryn Peterson, MD x, Wayne G. Shreffler, MD, PhD y, z, aa, Jonathan M. Spergel, MD, PhD p, q, Mary Jo Strobel bb, Joshua Wechsler, MD cc, Nives Zimmermann, MD h, Glenn T. Furuta, MD d, Marc E. Rothenberg, MD, PhD h a Mount Sinai Center for Eosinophilic Disorders, Icahn School of Medicine at Mount Sinai, New York, NY
b Division of Allergy, Asthma, and Clinical Immunology, Department of Medicine, Mayo Clinic Arizona, Scottsdale, Ariz
c Section of Allergy and Immunology, Division of Pulmonology, Phoenix Children’s Hospital, Phoenix, Ariz
d Children’s Hospital Colorado, University of Colorado School of Medicine, Aurora, Colo
e Rady Children’s Hospital, San Diego, Calif
f Division of Allergy, Immunology, University of California-San Diego, San Diego, Calif
g Department of Biochemistry and Molecular Genetics, College of Medicine, University of Illinois at Chicago, Chicago, Ill
h Cincinnati Children’s Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, Ohio
i Division of Allergy & Immunology, Center for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, NC
j Division of Immunology, Allergy, and Retrovirology, Baylor College of Medicine, Houston, Tex
k Texas Children’s Hospital Food Allergy Program, Texas Children’s Hospital, Houston, Tex
l Center for Esophageal Diseases and Swallowing, Division of Gastroenterology and Hepatology, University of North Carolina School of Medicine, Chapel Hill, NC
m Division of Gastroenterology and Hepatology, Feinberg School of Medicine, Chicago, Ill
n Department of Dermatology, School of Medicine, University of Utah School of Medicine, Salt Lake City, Utah
o Children’s of Alabama, University of Alabama at Birmingham, Birmingham, Ala
p Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pa
q Division of Allergy and Immunology, Children’s Hospital of Philadelphia, Philadelphia, Pa
r Wake Forest University School of Medicine, Winston-Salem, NC
s Division of Digestive and Liver Diseases, Columbia University Irving Medical Center, New York, NY
t Campaign Urging Research for Eosinophilic Disease, Lincolnshire, Ill
u Cincinnati Children’s Research Foundation, Division of Human Genetics, Center for Autoimmune Genomics and Etiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio
v Division of Allergy/Immunology, University of Arkansas for Medicine Sciences, Little Rock, Ark
w Arkansas Children’s Hospital, Little Rock, Ark
x Division of Gastroenterology, University of Utah Health, Salt Lake City, Utah
y Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, Mass
z Harvard Medical School, Massachusetts General Hospital, Boston, Mass
aa Food Allergy Center, Massachusetts General Hospital, Boston, Mass
bb American Partnership for Eosinophilic Disorders, Atlanta, Ga
cc Ann and Robert H. Lurie Children’s Hospital of Chicago, Chicago, Ill
∗Corresponding author: Mirna Chehade, MD, MPH, Mount Sinai Center for Eosinophilic Disorders, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1198, New York, NY 10029.Mount Sinai Center for Eosinophilic DisordersIcahn School of Medicine at Mount SinaiOne Gustave L. Levy PlaceBox 1198New YorkNY10029
Abstract |
The Consortium of Eosinophilic Gastrointestinal Diseases and The International Gastrointestinal Eosinophil Researchers organized a day-long symposium at the 2022 Annual Meeting of the American Academy of Allergy, Asthma & Immunology. The symposium featured a review of recent discoveries in the basic biology and pathogenesis of eosinophilic gastrointestinal diseases (EGIDs) in addition to advances in our understanding of the clinical features of EGIDs. Diagnostic and management approaches were reviewed and debated, and clinical trials of emerging therapies were highlighted. Herein, we briefly summarize the breakthrough discoveries in EGIDs.
Il testo completo di questo articolo è disponibile in PDF.Key words : Eosinophilic esophagitis, eosinophilic gastritis, eosinophil, food allergy
Abbreviations used : CEGIR, EED, EGID, EG-REFS, EoC, EoE, EoEHSS, EoG, EoN, eos/hpf, FDA, OIT, SCIT
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© 2023
American Academy of Allergy, Asthma & Immunology. Tutti i diritti riservati.
Vol 152 - N° 6
P. 1382-1393 - dicembre 2023 Ritorno al numero
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