Guidelines of care for the management of acne vulgaris - 11/04/24

Doi : 10.1016/j.jaad.2023.12.017

Rachel V. Reynolds, MD (Co-Chair) ^a, Howa Yeung, MD, MSc ^b, Carol E. Cheng, MD ^c, Fran Cook-Bolden, MD ^d, Seemal R. Desai, MD ^e,^f, Kelly M. Druby, BSN ^g, Esther E. Freeman, MD, PhD ^h, Jonette E. Keri, MD, PhD ^i,^j, Linda F. Stein Gold, MD ^k, Jerry K.L. Tan, MD ^l,^m, Megha M. Tollefson, MD ⁿ, Jonathan S. Weiss, MD ^b,^o, Peggy A. Wu, MD, MPH ^p, Andrea L. Zaenglein, MD ^q, Jung Min Han, PharmD, MS ^r,^⁎ , John S. Barbieri, MD, MBA (Co-Chair) ^s
^a Department of Dermatology, Beth Israel Deaconess Medical Center, Boston, Massachusetts
^b Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia
^c Division of Dermatology, Department of Medicine, University of California Los Angeles, Los Angeles, California
^d Department of Dermatology, Weill Cornell Medicine, New York, New York
^e Innovative Dermatology, Plano, Texas
^f Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas
^g Penn State Health Hampden Medical Center, Enola, Pennsylvania
^h Department of Dermatology, Massachusetts General Hospital, Boston, Massachusetts
ⁱ University of Miami, Miller School of Medicine, Miami, Florida
^j Miami VA Medical Center, Miami, Florida
^k Department of Dermatology, Henry Ford Health, Detroit, Michigan
^l Western University, London, Ontario, Canada
^m Windsor Clinical Research Inc., Windsor, Ontario, Canada
ⁿ Departments of Dermatology and Pediatrics, Mayo Clinic, Rochester, Minnesota
^o Georgia Dermatology Partners, Snellville, Georgia
^p Department of Dermatology, University of California Davis, Sacramento, California
^q Departments of Dermatology and Pediatrics, Penn State/Hershey Medical Center, Hershey, Pennsylvania
^r American Academy of Dermatology, Rosemont, Illinois
^s Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts

^∗Correspondence to: Jung Min Han, PharmD, MS, American Academy of Dermatology, 9500 Bryn Mawr Ave, Suite 500, Rosemont, IL 60018.American Academy of Dermatology9500 Bryn Mawr AveSuite 500RosemontIL60018

Abstract

Background

Acne vulgaris commonly affects adults, adolescents, and preadolescents aged 9 years or older.

Objective

The objective of this study was to provide evidence-based recommendations for the management of acne.

Methods

A work group conducted a systematic review and applied the Grading of Recommendations, Assessment, Development, and Evaluation approach for assessing the certainty of evidence and formulating and grading recommendations.

Results

This guideline presents 18 evidence-based recommendations and 5 good practice statements. Strong recommendations are made for benzoyl peroxide, topical retinoids, topical antibiotics, and oral doxycycline. Oral isotretinoin is strongly recommended for acne that is severe, causing psychosocial burden or scarring, or failing standard oral or topical therapy. Conditional recommendations are made for topical clascoterone, salicylic acid, and azelaic acid, as well as for oral minocycline, sarecycline, combined oral contraceptive pills, and spironolactone. Combining topical therapies with multiple mechanisms of action, limiting systemic antibiotic use, combining systemic antibiotics with topical therapies, and adding intralesional corticosteroid injections for larger acne lesions are recommended as good practice statements.

Limitations

Analysis is based on the best available evidence at the time of the systematic review.

Conclusions

These guidelines provide evidence-based recommendations for the management of acne vulgaris.

Il testo completo di questo articolo è disponibile in PDF.

Key words : Acne, acne vulgaris, adapalene, antiandrogens, antibiotics, azelaic acid, azithromycin, benzoyl peroxide, clascoterone, clindamycin, contraceptives, corticosteroids, Cutibacterium acnes, diet and acne, doxycycline, erythromycin, grading and classification of acne, guidelines, hormonal therapy, isotretinoin, light therapies, microbiological and endocrine testing, minocycline, retinoids, salicylic acid, sarecycline, spironolactone, tazarotene, treatment, tretinoin, trifarotene

Abbreviations used : AAD, BP, COC, EE, FDA, IBD, IGA, MD, RCT, RR, US, VTE

Mappa

	Funding sources: This study was funded in total by internal funds from the American Academy of Dermatology.
	Note: The “Executive summary: Guidelines of care for the management of acne vulgaris” is available as supplementary material.

Esportazione

Vol 90 - N° 5

P. 1006.e1-1006.e30 - maggio 2024 Ritorno al numero

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Guidelines of care for the management of acne vulgaris - 11/04/24

Abstract

Background

Objective

Methods

Results

Limitations

Conclusions

Mappa

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