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Comparison between artificial intelligence solution and radiologist for the detection of pelvic, hip and extremity fractures on radiographs in adult using CT as standard of reference - 14/01/25

Doi : 10.1016/j.diii.2024.09.004 
Maxime Pastor a, 1, , Djamel Dabli a, 1, Raphaël Lonjon a, Chris Serrand b, Fehmi Snene a, Fayssal Trad a, Fabien de Oliveira a, Jean-Paul Beregi a, Joël Greffier a
a IMAGINE UR UM 103, Montpellier University, Department of Medical Imaging, Nîmes University Hospital, 30900 Nîmes, France 
b Department of Biostatistics, Epidemiology, Public Health and Innovation in Methodology, Nîmes University Hospital, Univ. Montpellier, 30900 Nîmes, France 

Corresponding author.

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Highlights

The diagnostic performance of an artificial intelligence (AI) solution for the detection of pelvic, hip and extremity fractures on radiographs in adult was compared with that of a radiologist.
The AI solution achieved a sensitivity of 82 % and a specificity of 69 % which were both significantly lower than those obtained by the radiologist (92 % and 88 %, respectively).
The presence of a substantial number of false negative findings with the AI solution underscores the critical role of the radiologist in the diagnosis of these fractures in adult on radiographs.

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Abstract

Purpose

The purpose of this study was to compare the diagnostic performance of an artificial intelligence (AI) solution for the detection of fractures of pelvic, proximal femur or extremity fractures in adults with radiologist interpretation of radiographs, using standard dose CT examination as the standard of reference.

Materials and methods

This retrospective study included 94 adult patients with suspected bone fractures who underwent a standard dose CT examination and radiographs of the pelvis and/or hip and extremities at our institution between January 2022 and August 2023. For all patients, an AI solution was used retrospectively on the radiographs to detect and localize bone fractures of the pelvis and/or hip and extremities. Results of the AI solution were compared to the reading of each radiograph by a radiologist using McNemar test. The results of standard dose CT examination as interpreted by a senior radiologist were used as the standard of reference.

Result

A total of 94 patients (63 women; mean age, 56.4 ± 22.5 [standard deviation] years) were included. Forty-seven patients had at least one fracture, and a total of 71 fractures were deemed present using the standard of reference (25 hand/wrist, 16 pelvis, 30 foot/ankle). Using the standard of reference, the analysis of radiographs by the AI solution resulted in 58 true positive, 13 false negative, 33 true negative and 15 false positive findings, yielding 82 % sensitivity (58/71; 95 % confidence interval [CI]: 71–89 %), 69 % specificity (33/48; 95 % CI: 55–80 %), and 76 % accuracy (91/119; 95 % CI: 69–84 %). Using the standard of reference, the reading of the radiologist resulted in 65 true positive, 6 false negative, 42 true negative and 6 false positive findings, yielding 92 % sensitivity (65/71; 95 % CI: 82–96 %), 88 % specificity (42/48; 95 % CI: 75–94 %), and 90 % accuracy (107/119; 95 % CI: 85–95 %). The radiologist outperformed the AI solution in terms of sensitivity ( P = 0.045), specificity ( P = 0.016), and accuracy ( P < 0.001).

Conclusion

In this study, the radiologist outperformed the AI solution for the diagnosis of pelvic, hip and extremity fractures of the using radiographs. This raises the question of whether a strong standard of reference for evaluating AI solutions should be used in future studies comparing AI and human reading in fracture detection using radiographs.

Il testo completo di questo articolo è disponibile in PDF.

Keywords : Artificial intelligence, Computed tomography, Emergency radiology, Fracture, Radiograph

Abbreviations : AI, CI, CT, SD, ULD


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© 2024  Société française de radiologie. Pubblicato da Elsevier Masson SAS. Tutti i diritti riservati.
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Vol 106 - N° 1

P. 22-27 - gennaio 2025 Ritorno al numero
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