Republication de : Pleomorphic hyalinizing angiectatic tumor originating in the nasal cavity: A CARE case report - 25/01/25

Doi : 10.1016/j.aforl.2025.01.003

S. Sun ^a,^{^{1
These authors contributed equally to this work.}}, D. Que ^b,^{^{1
These authors contributed equally to this work.}}, B. Pan ^c, K. Hu ^a,⁎
^a Department of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 1 Shuaifuyuan Wangfujing, Dongcheng District, Beijing 100730, People's Republic of China
^b Department of Oncology, The Third Affiliated Hospital of Chongqing Medical University, Chongqing 401120, People's Republic of China
^c Molecular Pathology Research Center, Department of Pathology, Peking Union Medical College Hospital (PUMCH), Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, People's Republic of China

^∗Corresponding author.

Abstract

Introduction

Pleomorphic hyalinizing angiectatic tumor (PHAT) is a rare low-grade malignant mesenchymal neoplasm. It commonly occurs in the limbs and trunk, with limited occurrences in the head and neck region. Only five cases of PHAT occurring in the head and neck have been reported in the literature to date. The etiology of PHAT remains unclear. We described a case of nasal cavity PHAT following CARE guidelines.

Case summary

A 32-year-old male with PHAT originating in the nasal cavity recurred after two surgeries. Adjuvant radiotherapy was performed after the third surgery. The patient has been regularly followed up for 36months, and no tumor recurrence or metastasis has been observed.

Discussion

PHAT is a rare soft tissue tumor known for its local aggressiveness. Because of a high risk of recurrence, extensive resection should be implemented, possibly completed by radiotherapy if resection cannot be complete because of proximity to at-risk structures.

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Keywords : Nasal cavity tumors, Pleomorphic hyaline angiectatic tumor, Radiation therapy

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☆

Cet article a fait l’objet d’une première publication dans les European Annals of Otorhinolaryngology, Head and Neck Diseases. Nous le republions ici dans les pages des Annales Françaises d’Otolaryngologie, son titre jumelé. Avec autorisation de l’éditeur. Pour la citation veuillez utiliser la référence de la première parution : European Annals of Otorhinolaryngology, Head and Neck Diseases, 142 (1) (2025) 41–44. https://doi.org/10.1016/j.anorl.2024.05.003.

Esportazione

Vol 142 - N° 1

P. 42-44 - febbraio 2025 Ritorno al numero

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Republication de : Pleomorphic hyalinizing angiectatic tumor originating in the nasal cavity: A CARE case report - 25/01/25

Abstract

Introduction

Case summary

Discussion

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