NeuroFusion: A forensic enriched ensemble framework for cerebellum disease classification - 07/01/26

Doi : 10.1016/j.neuri.2025.100251 
Abu Hanzala a, , Md Sajjad b, Tanjila Akter a, Harpreet Kaur c, Md Sadekur Rahman a
a Department of Computer Science and Engineering, Daffodil International University, Bangladesh 
b Information and Communications Technology, School of Computer, Western Sydney University, Australia 
c Project Portfolio Lead, NouveauTech Consulting, Australia 

Corresponding author.

Benvenuto su EM|consulte, il riferimento dei professionisti della salute.
Articolo gratuito.

Si connetta per beneficiarne

Abstract

Accurate and timely classification of cerebellar diseases is crucial for effective diagnostic, yet it remains challenging due to the inherent heterogeneity of these disorders and the subtlety of their neuroimaging manifestations. This study investigated a novel multi-stage ensemble framework integrating SE blocks and segmentation-assisted augmentation tailored for limited cerebellum disease MRI data. Dataset included 3296 MRI scans from four classes and we divided dataset into three parts: training, testing, and validation, and their ratio was 64:20:16. However, we performed image forensic analysis on it, such as Error Level Analysis (ELA) and Noise Residual Analysis (NRA). This study used deep learning architectures that can automatically classify cerebellum diseases and compared these models, which included six D-CNNs models, six transfer learning models, and three ensemble models. Another important contribution of our study is the significant improvement in the classification efficiency by strategically integrating squeeze and excitation and label smoothing techniques. We show that fine-tuning significantly improves the diagnostic accuracy of both D-CNNs and transfer learning models on cerebellum MRI data. Notably, our combined models consistently achieve higher performance, with FusionNet-6 reaching an exceptional accuracy of 99.83 %. K-fold cross-validation was performed, yielding consistently high performance with per-class sensitivity and specificity above 99 %. The study also greatly enhances the impact of dataset augmentation techniques, including the use of segmented data to reveal complex interactions that can enhance the performance of some models or, in some cases, dramatically reduce the performance of specific models. These results underscore the immense potential of deep learning ensembles to provide highly accurate and robust diagnostic support for cerebellum diseases, paving the way for more objective and efficient clinical workflows.

Il testo completo di questo articolo è disponibile in PDF.

Highlights

A comprehensive evaluation of six D-CNNs, six transfer learning models, and three ensemble methods for cerebellar disease classification using MRI.
The dataset was enhanced through augmentation and segmentation, followed by forensic validation using ELA and NRA techniques.
Integration of squeeze-and-excitation and label smoothing significantly improved model performance.
FusionNet-6 ensemble model achieved an outstanding classification accuracy of 99.83 %.
Findings show that combining augmented and segmented data improves performance, while revealing degradation in some models.

Il testo completo di questo articolo è disponibile in PDF.

Keywords : Cerebellum disease classification, Brain disease classification, Squeeze-and-excitation network, Label smoothing, Deep learning, Convolutional neural network, Ensemble learning, D-CNN, Transfer learning


Mappa


© 2026  The Authors. Pubblicato da Elsevier Masson SAS. Tutti i diritti riservati.
Aggiungere alla mia biblioteca Togliere dalla mia biblioteca Stampare
Esportazione

    Citazioni Export

  • File

  • Contenuto

Vol 6 - N° 1

Articolo 100251- marzo 2026 Ritorno al numero
Articolo precedente Articolo precedente
  • Spatiotemporal dynamics of TMS-Evoked responses: A dual damped sine model analysis of cortical site and stimulation condition effects
  • Damián Jan
| Articolo seguente Articolo seguente
  • Exploring the effects of wavelet types and windowing on EMG-based IONM through deep learning architectures
  • Abdalla Nabil Elsharkawy, Nourhan Zayed

Benvenuto su EM|consulte, il riferimento dei professionisti della salute.

@@150455@@ Voir plus

Il mio account


Dichiarazione CNIL

EM-CONSULTE.COM è registrato presso la CNIL, dichiarazione n. 1286925.

Ai sensi della legge n. 78-17 del 6 gennaio 1978 sull'informatica, sui file e sulle libertà, Lei puo' esercitare i diritti di opposizione (art.26 della legge), di accesso (art.34 a 38 Legge), e di rettifica (art.36 della legge) per i dati che La riguardano. Lei puo' cosi chiedere che siano rettificati, compeltati, chiariti, aggiornati o cancellati i suoi dati personali inesati, incompleti, equivoci, obsoleti o la cui raccolta o di uso o di conservazione sono vietati.
Le informazioni relative ai visitatori del nostro sito, compresa la loro identità, sono confidenziali.
Il responsabile del sito si impegna sull'onore a rispettare le condizioni legali di confidenzialità applicabili in Francia e a non divulgare tali informazioni a terzi.


Tutto il contenuto di questo sito: Copyright © 2026 Elsevier, i suoi licenziatari e contributori. Tutti i diritti sono riservati. Inclusi diritti per estrazione di testo e di dati, addestramento dell’intelligenza artificiale, e tecnologie simili. Per tutto il contenuto ‘open access’ sono applicati i termini della licenza Creative Commons.