Cutaneous leukocytoclastic vasculitis leading to extensive digital necrosis as the only COVID-19 clinical manifestation - 26/03/26
Doi : 10.1016/j.vasdi.2025.12.003
Romane Pouy 1, Messaline Bermejo 1, Anne Durlach 2, Firouzé Bani-Sadr 1, ⁎ 
1 Department of Internal Medicine, Infectious Diseases, and Clinical Immunology, University Hospital of Reims, Reims, France
2 Department of Pathology, University Hospital of Reims, Reims, France
⁎ Corresponding author. Department of Internal Medicine, Infectious Diseases, and Clinical Immunology, CHU Robert-Debré, avenue du Général Koenig, 51092 Reims, France. Department of Internal Medicine, Infectious Diseases, and Clinical Immunology, CHU Robert-Debré avenue du Général Koenig Reims 51092 France
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Abstract |
Digital necrosis is now a well-established complication of COVID-19 infection, but data are sparse regarding the pathophysiology. We present the case of digital necrosis secondary to cutaneous leukocytoclastic vasculitis in a patient with COVID-19 infection. After histologic confirmation of vasculitis, the patient was given methylprednisolone leading to an improvement that enabled limited amputation.
Il testo completo di questo articolo è disponibile in PDF.Keywords : COVID-19 infection, Digital necrosis, Cutaneous leukocytoclastic vasculitis
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© 2025
Elsevier Masson SAS. Tutti i diritti riservati.
Vol 51 - N° 2
P. 97-99 - aprile 2026 Ritorno al numero
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