Mohs micrographic surgery histopathology concordance - 08/08/11
Reprint requests: David J. Leffell, MD, Yale Dermatologic Surgery, Yale School of Medicine, 40 Temple St, 5th Floor, Suite 5A, New Haven, CT 06510.Abstract |
Background |
The low recurrence rate and tissue-sparing benefit associated with Mohs micrographic surgery (MMS) requires accurate interpretation of frozen sections by the MMS surgeon.
Objective |
We sought to assess concordance between dermatopathologists and MMS surgeons when reporting cutaneous malignancy in the MMS setting.
Methods |
This study is a retrospective analysis of 1156 slides submitted during 10 years as part of a pre-existing randomized, blinded, quality assurance protocol. Slides were read by one of 5 dermatopathologists and represent cases from 3 MMS surgeons and 5 MMS fellows. Agreement or disagreement was recorded.
Results |
Of the 1156 slides, 32 slides (2.8%) were disparate. Aside from differences regarding intraepidermal neoplasia, the concordance rate was 99.7%.
Limitations |
This study represents data collected at a single institution in the United States alone.
Conclusion |
There was statistically significant concordance between MMS surgeons and dermatopathologists in frozen section interpretation in the MMS setting. Discordance was primarily related to the interpretation of in situ malignancy.
Il testo completo di questo articolo è disponibile in PDF.Abbreviations used : AK, BCC, IS, MMS, SCC
Mappa
| Supported by a National Institutes of Health postdoctoral research fellowship to Dr Mariwalla (2 T32 AR007016-32). |
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| Conflicts of interest: None declared. |
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| Presented at the Mohs College 2007 Annual Meeting in Naples, Florida, on May 3-6, 2007. |
Vol 60 - N° 1
P. 94-98 - gennaio 2009 Ritorno al numero
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