Acquired ichthyosis - 09/08/11
Reprint requests: Matthew J. Zirwas, MD, Department of Dermatology, University of Pittsburgh School of Medicine, 3601 Fifth Ave, Fifth Floor, Pittsburgh, PA 15213.Washington, District of Columbia, and Pittsburgh, Pennsylvania
Abstract |
Acquired ichthyosis (AI) is a nonhereditary cutaneous disorder characterized by dry, rough skin with prominent scaling that involves significant portions of the body. It has been associated with malignancies; autoimmune/inflammatory, metabolic, endocrine, and infectious diseases; and medication use. Most microscopic studies of AI exhibit hyperkeratosis with a reduced or absent granular layer. Because AI has been linked to a variety of conditions, the workup of a patient presenting with this finding can be complex. We present an update on AI to provide clinicians with direction regarding the assessment and treatment of patients presenting with AI. An algorithm for the evaluation of patients presenting with AI is provided.
Il testo completo di questo articolo è disponibile in PDF.Abbreviations used : AI, CTCL, DM, EGR, GVHD, HTLV, IV, SLE
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| Funding sources: None. Conflicts of interest: None identified. |
Vol 55 - N° 4
P. 647-656 - ottobre 2006 Ritorno al numero
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