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Nonampullary duodenal polyps: characteristics and endoscopic management - 22/08/11

Doi : 10.1016/j.gie.2009.11.043 
Rami Abbass, MD a, Johanne Rigaux, MD b, Firas H. Al-Kawas, MD a,
a Division of Gastroenterology, Georgetown University Hospital, Washington, District of Columbia, USA 
b Division of Gastroenterology, Erasme University Hospital, Brussels, Belgium 

Reprint requests: Firas H. Al-Kawas, MD, Chief of Endoscopy, Georgetown University Hospital, 3800 Reservoir Rd, NW, Washington, DC 20007

Riassunto

Background

Guidelines for endoscopic resection and surveillance of nonampullary duodenal (NAD) polyps are still not well-defined.

Objective

To describe the characteristics of NAD polyps and evaluate the role of endoscopic management.

Design

Retrospective review.

Setting

Tertiary-care academic center.

Patients

This study involved 59 patients with NAD polyps.

Intervention

Endoscopic polypectomy, biopsy, and argon plasma coagulation.

Main Outcome Measurements

Complete polypectomy, complications, and recurrence.

Results

Ninety-six endoscopies were performed. The mean patient age was 62.8 years. The mean (± standard deviation) polyp size was 17.2 mm ± 1.6 mm. The mean follow-up time was 26 months. Most lesions were sessile, solitary, and located in the descending duodenum. The procedure most often performed was submucosal injection followed by snare polypectomy. Adenomas were found in 68% of lesions overall and in 84% of lesions >2 cm. Successful resection was accomplished in 93% of cases on the initial attempt. Multiple endoscopies were needed in 5% of cases. The overall complete resection rate was 98%. Recurrence was documented in 37% of cases. Complications occurred in 5.2% of patients. Polyps of >2 cm were associated with higher rates of adenoma and a higher incidence of recurrence. Colon adenomas were found in 53% of patients with duodenal adenomas.

Limitations

Retrospective review. Not all patients underwent colonoscopy.

Conclusion

NAD polyps were large, sessile, and more commonly found in the second portion of the duodenum. They are more likely to be adenomatous when the lesion size is >2 cm. Despite successful endoscopic management, over one third of lesions demonstrated recurrence.

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Abbreviations : APC, NAD


Mappa


 DISCLOSURE:All authors disclosed no financial relationships relevant to this publication.
 See CME section; p. 824
 If you would like to chat with an author of this article, you may contact Dr Al-Kawas at alkawasf@gunet.georgetown.edu.


© 2010  American Society for Gastrointestinal Endoscopy. Pubblicato da Elsevier Masson SAS. Tutti i diritti riservati.
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