Endoscopic and oncologic outcomes after endoscopic resection for early gastric cancer: 1370 cases of absolute and extended indications - 27/08/11
Reprint requests: Hwoon-Yong Jung, MD, PhD, AGAF, Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Asan Digestive Disease Research Institute, No. 388-1 Pungnap-2 dong, Songpa-gu, Seoul, 138-736, KoreaRiassunto |
Background |
Current guidelines for endoscopic management such as EMR and endoscopic submucosal dissection (ESD) in early gastric cancer (EGC) are in evolution, with broader indication criteria.
Objective |
To determine the clinical outcomes of endoscopic treatment, based on absolute indication and extended indication criteria and endoscopic methods.
Design |
Retrospective study.
Setting |
Tertiary-care, academic medical center.
Patients |
EMR or ESD was performed on 1627 cases of EGC in 1447 patients from July 1994 to January 2009.
Intervention |
EMR and ESD.
Main Outcome Measurements |
Clinical outcomes of EGC after EMR or ESD, based on the indication criteria.
Results |
Although the complete resection rate was higher (95.9% vs 88.4%; P < .001), and the complication rate was lower (6.8% vs 9.8%; P = .054) in the absolute than in the extended indication group, there was no between-group difference in the local recurrence rate (0.9% vs 1.1%; P = .783) at a median follow-up period of 32 months (interquartile range 22-48 months). In the extended indication group, ESD resulted in a significantly higher complete resection rate than EMR (83.0% vs 91.1%; P = .006).
Limitations |
Retrospective study.
Conclusion |
ESD in the extended indication group showed acceptable clinical outcomes with a relatively high complete resection rate and a low local recurrence rate.
Il testo completo di questo articolo è disponibile in PDF.Abbreviations : EGC, ESD
Mappa
| DISCLOSURE: All authors disclosed no financial relationships relevant to this publication. |
Vol 74 - N° 3
P. 485-493 - settembre 2011 Ritorno al numero
Articolo precedente
- Long-term outcome of transoral organ-preserving pharyngeal endoscopic resection for superficial pharyngeal cancer
- Manabu Muto, Hironaga Satake, Tomonori Yano, Keiko Minashi, Ryuichi Hayashi, Satoshi Fujii, Atsushi Ochiai, Atsushi Ohtsu, Shuko Morita, Takahiro Horimatsu, Yasumasa Ezoe, Shinichi Miyamoto, Ryo Asato, Ichiro Tateya, Akihiko Yoshizawa, Tsutomu Chiba
- Endoscopic resection for early gastric cancer: one piece is better than dash to pieces
- Philip Wai-yan Chiu, Joseph Jao-yiu Sung
Benvenuto su EM|consulte, il riferimento dei professionisti della salute.
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