Hypocomplementemic urticarial vasculitis with angioedema, a rare presentation of systemic lupus erythematosus: rapid response to rituximab - 29/08/11
Doi : 10.1016/S0190-9622(03)00744-8
Kapil Saigal, MD a, Isabel C Valencia, MD a, Jonathan Cohen, MD b, Francisco A Kerdel, MD a, ⁎
a Department of Dermatology and Cutaneous Surgery, University of Miami School of Medicine, Miami, Florida, USA
b Department of Hematology and Oncology, Cedars Medical Center, Miami, Florida, USA
*Correspondence to: Francisco A. Kerdel, MD, Cedars Medical Center, 1444 NW 12th Ave, 6 South Derm, Miami, FL 33136, USA.
Abstract |
We report a case of hypocomplementemic urticarial vasculitis and recurrent angioedema in a patient with systemic lupus erythematosus unresponsive to mycophenolate mofetil, high-dose methylprednisolone, and intravenous immunoglobulin that responded rapidly to rituximab. Rituximab is a monoclonal antibody against CD20 transmembrane protein on the surface of mature and malignant B cells. No adverse effects occurred during or after therapy, and the patient was discharged from the hospital for outpatient rituximab infusion and follow-up care.
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 | Funding sources: None. Conflict of interest: None identified. |
© 2003
American Academy of Dermatology, Inc.. Pubblicato da Elsevier Masson SAS. Tutti i diritti riservati.
Vol 49 - N° 5S
P. 283-285 - novembre 2003 Ritorno al numero
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