Autoimmune progesterone dermatitis manifested as erythema annulare centrifugum: Confirmation of progesterone sensitivity by in vitro interferon-γ release - 01/09/11
Doi : 10.1067/mjd.2002.121345
Sima Halevy, MDa, Arnon D. Cohen, MDa, Eitan Lunenfeld, MDb, Nili Grossman, PhDc
Beer-Sheva, Israel
From the Department of Dermatology,a the Department of Obstetrics and Gynecology,b and Investigative Dermatology Laboratory,c Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev
Abstract |
Autoimmune progesterone dermatitis was manifested as deep-type erythema annulare centrifugum. Sensitivity to progesterone was studied in vivo by means of intradermal and patch tests, which revealed immediate-type and delayed-type hypersensitivity, respectively. Sensitivity to progesterone was further confirmed in vitro by results of an interferon-γ release test, which imply a possible role for TH1-type cytokines in autoimmune progesterone dermatitis. (J Am Acad Dermatol 2002;47:311-3.)
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 | Funding sources: None. |
| Conflict of interest: None. |
 | Reprint requests: Sima Halevy, MD, Department of Dermatology, Soroka University Medical Center, Beer-Sheva 84101, Israel. |
© 2002
American Academy of Dermatology, Inc. Pubblicato da Elsevier Masson SAS. Tutti i diritti riservati.
Vol 47 - N° 2
P. 311-313 - agosto 2002 Ritorno al numero
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