Generalized hyperpigmentation with daunorubicin chemotherapy - 01/09/11
Doi : 10.1016/S0190-9622(02)70217-X
Abstract |
Daunorubicin has been reported to cause hyperpigmentation of sun-exposed skin and/or transverse nail pigmentation (3 cases). We report a case of an African American man who had an atypical pattern of generalized hyperpigmentation develop that involved many sun-protected skin areas 2 weeks after daunorubicin treatment. Histopathology of hyperpigmented skin showed increased melanin granules in all epidermal layers. The mechanisms by which daunorubicin may increase skin pigmentation are discussed. (J Am Acad Dermatol 2002;46:S1-3.)
Il testo completo di questo articolo è disponibile in PDF.Mappa
 | This supplement is made possible through an unrestricted educational grant from Stiefel Laboratories to the American Academy of Dermatology. |
| Reprint requests: George Kroumpouzos, MD, Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, 45 Francis St, Boston, MA 02115. E-mail: kroumpouzos.george@boston.va.gov. |
© 2002
American Academy of Dermatology, Inc. Pubblicato da Elsevier Masson SAS. Tutti i diritti riservati.
Vol 46 - N° 2S
P. S1-S3 - febbraio 2002 Ritorno al numero
Articolo seguente
- Treatment of warty dyskeratoma with tazarotenic acid
- William Abramovits, Nagla Abdelmalek
Benvenuto su EM|consulte, il riferimento dei professionisti della salute.
L'accesso al testo integrale di questo articolo richiede un abbonamento.
Già abbonato a @@106933@@ rivista ?