Traumatic osmium tetroxide inoculation - 02/09/11
Doi : 10.1067/mjd.2001.117392
Jeff J. Ligon, MDa, Jerrold L. Abraham, MDc, Alan S. Boyd, MDa,b
Nashville, Tennessee, and Syracuse, New York
From the Departments of Medicine (Dermatology)a and Pathology,b Vanderbilt University, and the Department of Veterans Affairs Medical Center, Nashville, and the Department of Pathology, State University of New York Upstate Medical University, Syracuse.c
Abstract |
Osmium tetroxide is a highly oxidizing, corrosive compound commonly found in electron microscopy laboratories. Although osmium tetroxide is known to cause rapid damage to organic tissue, its cutaneous effects have not been well studied. We report a case of traumatic inoculation from a broken vial of 4% osmium tetroxide. Electron microscopy and energy dispersive x-ray spectroscopy confirmed the presence of osmium in the tissue specimen. The lesion was treated by simple excision. (J Am Acad Dermatol 2001;45:949-52.)
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© 2001
American Academy of Dermatology, Inc. Pubblicato da Elsevier Masson SAS. Tutti i diritti riservati.
Vol 45 - N° 6
P. 949-952 - dicembre 2001 Ritorno al numero
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