VARICELLA VACCINE - 06/09/11
Riassunto |
The varicella-zoster virus (VZV) causes two distinct clinical diseases: varicella (chickenpox) and herpes zoster (shingles). Heberden first differentiated the two diseases in 1767, when he called chickenpox varicella, a diminutive form of the Latin variola (smallpox). The derivation of the term chickenpox is less clear. Some state that it derives from the Old English word gican, which meant “itch” and is pronounced with a soft g. Most authorities, however, believe that the allusion is to the chickpea, pois chiche in French.57 When sliced in half and laid on a pink-colored disc, the chickpea bears a remarkable resemblance to the characteristic erythematous vesicles seen in chickenpox.48 Herpes comes from the Greek herpes, “to creep.” The terms zoster and shingles derive from the respective Greek and Latin terms zoster and cingulum, for the “girdle”-like dermatomal distribution of the rash.
Weller and Stoddard74 first isolated virus in tissue culture from vesicle fluid of chickenpox and zoster in 1952. The viruses recovered were identical, and the name varicella zoster virus was given to the agent.
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| Address reprint requests to Stephen A. Chartrand, MD, Department of Pediatrics, Creighton University School of Medicine, Criss II, Room 409, 2500 California Plaza, Omaha, NE 68178 |
Vol 47 - N° 2
P. 373-394 - aprile 2000 Ritorno al numeroBenvenuto su EM|consulte, il riferimento dei professionisti della salute.
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