PANCREATIC EXOCRINE-ENDOCRINE INTERRELATIONSHIP : Clinical Implications - 08/09/11
Riassunto |
Disorders of the exocrine and endocrine pancreata constitute some of the most prevalent and life-threatening diseases affecting people today. Each year, approximately 20 in 100,000 people are diagnosed with chronic pancreatitis; 50,000 to 80,000 acute pancreatitis cases, 30,000 cystic fibrosis cases, 29,000 pancreatic cancer cases, and 16 million cases of diabetes occur in the United States.14, 16, 60, 63, 64 Exocrine pancreatic dysfunction often potentiates endocrine pancreatic dysfunction and vice versa because the endocrine and exocrine pancreata are anatomically and functionally interrelated. Elucidating the nature of these exocrine-endocrine interrelationships, therefore, has important implications for the clinical diagnosis and management of these diseases. This article focuses on the functions of the exocrine and endocrine pancreata, their interrelationships, and the role these interrelationships play in various pancreatic disorders.
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| Address Reprint Requests toVay Liang W. Go, MD, UCLA Center for Human Nutrition, Warren Hall, Room 13-146, 900 Veteran Avenue, Los Angeles, CA 90095, e-mail: vlwgo@ucla.edu |
Vol 28 - N° 3
P. 551-569 - settembre 1999 Ritorno al numero
Articolo precedente
- PANCREATITIS AND CYSTIC FIBROSIS GENE MUTATIONS
- Division of Gastroenterology/Hepatology, Indiana University Medical Center, Indianapolis, Indiana, C.P. Choudari, Glen A. Lehman, Stuart Sherman
- CAUSES OF ACUTE AND RECURRENT PANCREATITIS : Clinical Considerations and Clues to Diagnosis
- Department of Gastroenterology, Long Island Jewish Medical Center, New Hyde Park; and the Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, Simmy Bank, Anant Indaram
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