COATS' DISEASE AND PERSISTENT HYPERPLASTIC PRIMARY VITREOUS : Role of MR Imaging and CT - 09/09/11

Doi : 10.1016/S0033-8389(05)70235-9

Deepak P. Edward, MD ^a, Mahmood F. Mafee, MD, FACR ^c,^d,^e, Enrique Garcia-Valenzuela, MD, PhD ^b,^d, Robert A. Weiss, MD ^a

^a Department of Ophthalmology, University of Illinois Eye Center, University of Illinois College of Medicine (DPE, RAW)

^b Departments of Ophthalmology (EGV)

^c Radiology (MFM)

^d Eye and Ear Infirmary (MFM, EGV)

^e MR Imaging Center (MFM), The University of Illinois at Chicago, Chicago, Illinois

Riassunto

Coats' disease (primary retinal telangiectasis) is an idiopathic disorder characterized by telangiectatic and aneurysmal retinal vessels with progressive deposition of intraretinal and subretinal exudates that leads to massive exudative retinal detachment. George Coats^{9 Coats G. Forms of retinal dysplasia with massive exudation R Lond Ophthalmol Hosp Rep 1908 ; 17 : 440

Cliccare qui per andare alla sezione Riferimenti} made the first detailed description of this entity in 1908. With the development of fluorescein angiography, vascular abnormalities were demonstrated in the retina.

Gomez Morales^{22 Glasier C.M., Brodsky M.C., Leithiser R.E. High resolution ultrasound with Doppler: A diagnostic adjunct in orbital and ocular lesion in children Pediatr Radiol 1992 ; 22 : 174 [cross-ref]

Cliccare qui per andare alla sezione Riferimenti} classified Coats' disease in five stages, based on the severity of the abnormalities that resulted from the vascular changes. Stage 1 includes eyes with only focal exudates. In stage 2, eyes show massive intraretinal exudation. Eyes with stage 3 disease display partial exudative retinal detachment, whereas in stage 4 the retina is totally detached. Stage 5 includes eyes with complications secondary to chronic retinal detachment.^{53 Sigelman J. Retinal diseases: Pathogenesis, Laser Therapy and Surgery Boston: Little Brown (1984).
331

Cliccare qui per andare alla sezione Riferimenti} In addition, other classifications of Coats' disease have also been reported in the literature.^{20 Gass J.D.M., Oyakawa R.T. Idiopathic juxtafovel retinal telangiectasis Arch Ophthalmol 1982 ; 100 : 769

Cliccare qui per andare alla sezione Riferimenti, 53 Sigelman J. Retinal diseases: Pathogenesis, Laser Therapy and Surgery Boston: Little Brown (1984).
331

Cliccare qui per andare alla sezione Riferimenti, 61 Woods A.C., Duke J. Coats' disease I. Review of the literature, diagnostic criteria, clinical findings and plasma lipid studies Br J Ophthalmol 1963 ; 47 : 385 [cross-ref]

Cliccare qui per andare alla sezione Riferimenti, 62 Yanuzzi L.A., Gitter K.A., Schatz H. The Macula: A Comprehensive Text and Atlas Baltimore: Williams and Wilkins (1979).

Cliccare qui per andare alla sezione Riferimenti}

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CLINICAL PRESENTATION

HISTOPATHOLOGY

NATURAL COURSE AND TREATMENT

DIFFERENTIAL DIAGNOSIS

Address reprint requests to Deepak P. Edward, MD, Department of Ophthalmology, University of Illinois Eye Center, 1855 West Taylor Street, Chicago, IL 60612
Supported in part by Otsuka Research Fellowship from the American Glaucoma Society (DPE), a gift from The Laura K. Binder Fund (DPE), and a Departmental Care grant EY01792 from the National Institutes of Health, Bethesda, Maryland.

Esportazione

Vol 36 - N° 6

P. 1119-1131 - novembre 1998 Ritorno al numero

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COATS' DISEASE AND PERSISTENT HYPERPLASTIC PRIMARY VITREOUS : Role of MR Imaging and CT - 09/09/11

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