The abdominoperineal resection, first described by Miles <sup>71 Miles W.E. A method of performing abdominoperineal excision for carcinoma of the rectum and of the terminal portion of the pelvic colon Lancet 1908 ;  2 : 1812-1813

Cliccare qui per andare alla sezione Riferimenti</sup> in the early 1900s, has morbidity rates ranging between 50% and 75%.<sup>1 Altemeier W.A., Culbertson W.R., Alexander J.W. , e al. Primary closure and healing of the perineal wound in abdominoperineal resection of the rectum for carcinoma Am J Surg 1974 ;  127 : 215-219  [cross-ref]

Cliccare qui per andare alla sezione Riferimenti, 81 Rothenberger D.A., Wong W.D. Abdominoperineal resection for adenocarcinoma of the low rectum World J Surg 1992 ;  16 : 478-485  [cross-ref]

Cliccare qui per andare alla sezione Riferimenti</sup> In most series, perineal wound complications (16.5%) ranked second to urologic problems (21%) in overall frequency.<sup>81 Rothenberger D.A., Wong W.D. Abdominoperineal resection for adenocarcinoma of the low rectum World J Surg 1992 ;  16 : 478-485  [cross-ref]

Cliccare qui per andare alla sezione Riferimenti</sup> In inflammatory bowel disease (IBD), morbidity is even higher, ranging from 25% to 80%, <sup>14 Berry A.R., De Campos R., Lee E.C. Perineal and pelvic morbidity following perimuscular excision of the rectum for inflammatory bowel disease Br J Surg 1986 ;  73 : 675-677  [cross-ref]

Cliccare qui per andare alla sezione Riferimenti, 17 Broeders I.A., Poen H., Ottow R.T. Proctocolectomy with permanent ileostomy versus restorative proctocolectomy in ulcerative colitis; the past as background for the present Ned Tijdschr Geneeskd 1991 ;  27 : 1354-1358

Cliccare qui per andare alla sezione Riferimenti, 93 Strachan J., Wilson W., McMechan E.W. A review of surgically treated ulcerative colitis Ir J Med Sci 1967 ;  494 : 83

Cliccare qui per andare alla sezione Riferimenti</sup> with higher rates for Crohn's disease.<sup>106 Williams J.G., Hughes L.E. Abdominoperineal resection for severe perianal Crohn's disease Dis Colon Rectum 1990 ;  33 : 402-407  [cross-ref]

Cliccare qui per andare alla sezione Riferimenti</sup> In this report, the cause, prevention, and management of the most common perineal complications—(1) perineal infections and the failure of the perineal wound to heal; (2) the persistent perineal sinus tract; and (3) perineal herniation—are discussed.