Immunosuppressive Protocols and Immunological Challenges Related to Hand Transplantation - 02/11/11
Corresponding author.Riassunto |
There are many immunological challenges related to hand transplantation. Curbing the immune system's ability to effectively mount an immune response against the graft is the goal. As the various components of the immune response are defined and their mechanisms of action delineated, more specific immunosuppressive agents and protocols have been developed. Complications related to immunosuppression in hand transplant recipients are similar to incidences among solid organ recipients. With longer follow-up, the increased cardiovascular risk factors or the development of a neoplasm will likely cause mortality. Standardizing immunosuppression in hand transplantation with the long-term goal of minimization is critically needed.
Il testo completo di questo articolo è disponibile in PDF.Keywords : Hand transplant, Immunosuppression, Immunology, Vascularized composite allotransplantation
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| This work was supported in part by The Department of the Army, Office of Army Research. (Any opinions, findings, and conclusions or recommendations expressed in this material are those of the authors and do not necessarily reflect the views of the Office of Army Research.) This publication was made possible by Awards No. W81X WH07-1-0185, W81XWH-09-2-0124, and W81X WH10-1-0688 from the Office of Army Research); the Commonwealth of Kentucky Research Challenge Trust Fund; the W. M. Keck Foundation; and The Jewish Hospital Foundation. |
Vol 27 - N° 4
P. 467-479 - novembre 2011 Ritorno al numero
Articolo precedente
- Functional Outcome after Hand and Forearm Transplantation: What Can Be Achieved?
- Marina Ninkovic, Annemarie Weissenbacher, Markus Gabl, Gerhard Pierer, Johann Pratschke, Raimund Margreiter, Gerald Brandacher, Stefan Schneeberger
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