An endoscopic wireless gastrostimulator (with video) - 15/01/12
Reprint requests: Thomas L. Abell, MD, Division of Digestive Diseases, University of Mississippi Medical Center, Jackson, MS 39216Riassunto |
Background |
Gastric electric stimulation (GES) at a high-frequency, low-energy setting is an option for treating refractory gastroparesis. The currently available commercial stimulator, the Enterra neurostimulator (Medtronic Inc, Minneapolis, MN), however, requires surgical implantation and is powered by a nonrechargeable battery.
Objective |
To develop and test a miniature wireless GES device for endoscopic implantation in an experimental model.
Design |
In-vivo gastric signals were recorded and measured in a nonsurvival swine model (n = 2; 110-lb animals).
Intervention |
An endoscopically placed, wireless GES device was inserted into the stomach through an overtube; the two GES electrodes were endoscopically attached to the gastric mucosa and secured with endoclips to permit stimulation.
Main Outcome Measurements |
Stable electrogastrogram measures were observed during GES stimulation.
Results |
Electrogastrogram recordings demonstrated that gastric slow waves became more regular and of constant amplitudes when stomach tissues were stimulated, in comparison with no stimulation. The frequency-to-amplitude ratio also changed significantly with stimulation.
Limitation |
Nonsurvival pig studies.
Conclusion |
Gastric electric stimulation is feasible by our endoscopically implanted, wireless GES device.
Il testo completo di questo articolo è disponibile in PDF.Abbreviations : GES, EGG, GP, FAR
Mappa
| DISCLOSURE: The authors disclosed no financial relationships relevant to this publication. |
Vol 75 - N° 2
P. 411 - febbraio 2012 Ritorno al numero
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