The article provides an overview of the work on regio- and, in the occurrence, stereoselective tether-directed remote functionalization of fullerenes in the Diederich group, from the initial stages in 1994 to the present. All bisaddition patterns of C₆₀, except cis-1, have been realized with high selectivities, mainly by Bingel-type macrocyclizations. Particular emphasis is placed on the stereoselective generation of the inherently chiral cis-3, trans-3, and trans-2 addition patterns. Besides, one of the rare examples of direct threefold tether-directed cyclopropanation of C₆₀ is presented and the spacer-controlled derivatization of C₇₀ is reviewed. To cite this article: C. Thilgen, F. Diederich, C. R. Chimie 9 (2006).