Persons with cerebral palsy (CP) need to modify their lifestyle in order to carry out daily activities. Assistive technology facilitates communication and improves the domestic environment and mobility. The STARNAV Company has developed a Head Tracking System, Head Pilot, which uses a robust algorithm that measures, in real-time, head motion from a webcam. Head Pilot aims to control any informatic and domotic interface controlling the pointer of a PC. This work aims to create an assistive technology that is easy to use once it is set up and used. The system offers an interface control, which allows individual users to adjust the system for their comfort. The system displays a toolbar allowing the patient to choose the velocity of the pointer and to choose from several different ways to validate a task. The objective of this study was to evaluate the performance of Head Pilot by using five computerized tests of validation. Seven participants with disabilities were compared to seven participants with no relevant medical history (control group). Two versions of the software were developed and displayed on a computer screen. The time to complete the tests were measured and compared to a control group. Before testing, the disabled persons had received an orthoptic assessment, a cognitive evaluation, and a cervical motor check. Head Pilot was validated for use by the majority of users with CP who were able to control a computer except for the subject with incomplete locked-in syndrome, who required an Eye Tracker System.